SCHEMBL5992716

SCHEMBL5992716

C=CC[C@H]1CCN1C(=O)O

nearest known ligand 0.35

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ELANE P08246 7/20 0.35
CTSG P08311 3/20 0.35
F2 P00734 3/20 0.33
CHRNB2 P17787 1/20 0.33
CHRNB4 P30926 1/20 0.33
CHRNA3 P32297 1/20 0.33
CHRNA7 P36544 1/20 0.33
CHRNA4 P43681 1/20 0.33
DPP4 P27487 1/20 0.31
FAAH O00519 1/20 0.31
KMT2A Q03164 2/20 0.31
POLB P06746 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
MEN1 O00255 1/20 0.30
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27855134 0.89 POLB (0.44) CHRNB2CHRNB4CHRNA3CHRNA7CHRNA4
SCHEMBL29060151 0.89 POLB (0.44) CHRNB2CHRNB4CHRNA3CHRNA7CHRNA4
SCHEMBL7073933 0.87 CHRNB2 (0.40) CHRNB2CHRNB4CHRNA3CHRNA7CHRNA4
SCHEMBL2459930 0.83 HSD17B10 (0.33) ELANECTSGKMT2AMEN1
SCHEMBL20855368 0.83 ELANE (0.33) ELANECTSGCHRNB2CHRNB4CHRNA3
SCHEMBL19331341 0.83 ELANE (0.33) ELANECTSGF2DPP4
SCHEMBL8088904 0.82 ELANE (0.37) ELANECTSGF2CHRNB2CHRNB4
SCHEMBL17395506 0.82 POLB (0.31) POLBL3MBTL1
SCHEMBL21439770 0.77 CA1 (0.34) DPP4
SCHEMBL1502273 0.77 PDK1 (0.38) DPP4L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1654268-A2 LINCOMYCIN DERIVATIVES POSSESSING ANTIBACTERIAL ACTIVITY Vicuron Pharmaceuticals, Inc. (US) 2006-05-10 EP disclosed
EP-1644393-A2 NOVEL LINCOMYCIN DERIVATIVES POSSESSING ANTIMICROBIAL ACTIVITY Vicuron Pharmaceuticals, Inc. (US) 2006-04-12 EP disclosed
WO-2005012320-A2 NOVEL LINCOMYCIN DERIVATIVES POSSESSING ANTIMICROBIAL ACTIVITY VICURON PHARMACEUTICALS, INC. (US) 2005-02-10 WO disclosed
WO-2005007665-A2 LINCOMYCIN DERIVATIVES POSSESSING ANTIBACTERIAL ACTIVITY VICURON PHARMACEUTICALS INC. (US) 2005-01-27 WO disclosed