Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 7/20 | 0.86 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.84 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.84 |
| ▸ | TP53 | P04637 | 8/20 | 0.84 |
| ▸ | LMNA | P02545 | 5/20 | 0.79 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.75 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.75 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.71 |
| ▸ | MEN1 | O00255 | 1/20 | 0.71 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.71 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.71 |
| ▸ | TSHR | P16473 | 1/20 | 0.68 |
| ▸ | MAPT | P10636 | 1/20 | 0.68 |
| ▸ | THRB | P10828 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16896188 | 0.85 | POLB (0.76) | POLBKMT2AALDH1A1TP53LMNA | |
| SCHEMBL20096187 | 0.83 | ALDH1A1 (0.85) | POLBKMT2AALDH1A1TP53LMNA | |
| SCHEMBL16903565 | 0.80 | MAPT (0.80) | TP53LMNARXFP1MAPTTHRB | |
| SCHEMBL16896230 | 0.79 | TP53 (0.73) | POLBKMT2AALDH1A1TP53LMNA | |
| SCHEMBL16896033 | 0.78 | LMNA (0.70) | POLBALDH1A1TP53LMNAMAPT | |
| SCHEMBL16903570 | 0.78 | MAPT (0.66) | POLBKMT2AALDH1A1TP53LMNA | |
| SCHEMBL16896219 | 0.78 | LMNA (0.82) | POLBKMT2ATP53LMNAMEN1 | |
| SCHEMBL16896049 | 0.78 | LMNA (0.85) | POLBKMT2ATP53LMNAMEN1 | |
| SCHEMBL16896209 | 0.77 | LMNA (0.87) | POLBKMT2ATP53LMNAMEN1 | |
| SCHEMBL16896100 | 0.77 | LMNA (0.87) | POLBKMT2ATP53LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012065139-A2 | ENTPD5 INHIBITORS | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2012-05-18 | — | — | WO | disclosed |