Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP5 | Q13451 | 1/20 | 0.73 |
| ▸ | NAPRT | Q6XQN6 | 2/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | DAO | P14920 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetone SCHEMBL27901178 | 0.93 | FKBP5 (0.76) | FKBP5NAPRTNOTUMCES2CES1 | |
| Acetamide SCHEMBL7526547 | 0.89 | FKBP5 (0.70) | FKBP5NAPRTNOTUMDAOHSD17B10 | |
| Methyl Alcohol SCHEMBL28775298 | 0.88 | — | — | |
| Benzene SCHEMBL28121469 | 0.88 | FKBP5 (0.94) | FKBP5NAPRTNOTUMDAOHSD17B10 | |
| Ethane SCHEMBL5943177 | 0.85 | — | — | |
| SCHEMBL9596 | 0.85 | — | — | |
| SCHEMBL27324502 | 0.85 | FKBP5 (1.00) | FKBP5NAPRTNOTUMDAOKDM4E | |
| Acetic Acid SCHEMBL7131593 | 0.85 | FKBP5 (0.64) | FKBP5NAPRTNOTUMCES2CES1 | |
| Acetic Acid SCHEMBL7131592 | 0.85 | FKBP5 (0.64) | FKBP5NAPRTNOTUMCES2CES1 | |
| Acetic Acid SCHEMBL9604109 | 0.84 | FKBP5 (0.52) | FKBP5NAPRTNOTUMSMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060151007-A1 | Workpiece processing using ozone gas and chelating agents | SEMITOOL, INC. | 2006-07-13 | — | — | US | claimed |
| CN-116925069-B | Synthesis method of iron-catalyzed fused ring [1,2-a ] indole compound | 湖北工程学院 | 2025-03-28 | — | — | CN | disclosed |
| US-20060151007-A1 | Workpiece processing using ozone gas and chelating agents | SEMITOOL, INC. | 2006-07-13 | — | — | US | disclosed |