Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3A | P49840 | 1/20 | 0.67 |
| ▸ | GSK3B | P49841 | 1/20 | 0.67 |
| ▸ | IGF1R | P08069 | 1/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.58 |
| ▸ | MEN1 | O00255 | 7/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.58 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.52 |
| ▸ | MITF | O75030 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.50 |
| ▸ | G6PD | P11413 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.50 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3771633 | 0.91 | GSK3A (0.80) | GSK3AGSK3BIGF1RKMT2AMEN1 | |
| SCHEMBL5463774 | 0.83 | GSK3A (0.68) | GSK3AGSK3BIGF1RKMT2AMEN1 | |
| SCHEMBL31358728 | 0.81 | GSK3A (0.59) | GSK3AGSK3BIGF1RKMT2AMEN1 | |
| SCHEMBL3907981 | 0.79 | IGF1R (0.81) | GSK3AGSK3BIGF1RDUSP3ITGB2 | |
| SCHEMBL3907984 | 0.79 | IGF1R (0.81) | GSK3AGSK3BIGF1RDUSP3ITGB2 | |
| SCHEMBL10018549 | 0.79 | KMT2A (0.74) | KMT2AMEN1L3MBTL1MITFNPSR1 | |
| SCHEMBL12632706 | 0.78 | GSK3A (0.61) | GSK3AGSK3BIGF1RKMT2AMEN1 | |
| SCHEMBL5147292 | 0.75 | PIK3CG (0.71) | GSK3AGSK3BKMT2AMEN1L3MBTL1 | |
| SCHEMBL16924933 | 0.73 | GSK3A (0.54) | GSK3AGSK3BIGF1RKMT2AMEN1 | |
| SCHEMBL5168146 | 0.72 | KMT2A (0.69) | GSK3AGSK3BIGF1RKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012065139-A2 | ENTPD5 INHIBITORS | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2012-05-18 | — | — | WO | disclosed |