Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3096665 | 0.81 | ALDH1A1 (0.55) | TSHRALDH1A1CYP1A2MEN1KMT2A | |
| SCHEMBL598437 | 0.80 | CPA1 (0.54) | CYP1A2 | |
| SCHEMBL598436 | 0.80 | CPA1 (0.54) | CYP1A2 | |
| SCHEMBL10668707 | 0.78 | ALDH1A1 (0.51) | TSHRALDH1A1CYP1A2MEN1KMT2A | |
| SCHEMBL258592 | 0.78 | ALDH1A1 (0.51) | TSHRALDH1A1CYP1A2MEN1KMT2A | |
| SCHEMBL258742 | 0.78 | ALDH1A1 (0.51) | TSHRALDH1A1CYP1A2MEN1KMT2A | |
| SCHEMBL15226929 | 0.77 | POLB (0.51) | TSHRALDH1A1MEN1KMT2A | |
| SCHEMBL8977587 | 0.77 | ALPI (0.51) | TSHRALDH1A1CYP1A2 | |
| SCHEMBL7424434 | 0.77 | POLB (0.51) | TSHRALDH1A1MEN1KMT2A | |
| SCHEMBL10667965 | 0.77 | ALDH1A1 (0.54) | TSHRALDH1A1CYP1A2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8114648-B2 | In vivo incorporation of unnatural amino acids | THE SCRIPPS RESEARCH INSTITUTE (US) | 2012-02-14 | — | — | US | claimed |
| US-20080167243-A1 | immunizing a subject with a sufficient amount of a translated polypeptide to produce antibody; containing a phenylalanine or tyrosine derivative analoges | THE SCRIPPS RESEARCH INSTITUTE | 2008-07-10 | — | — | US | claimed |
| EP-1154802-A1 | METHOD OF MEASURING PHYSIOLOGICAL FUNCTION | Mallinckrodt Inc. (US) | 2001-11-21 | — | — | EP | claimed |
| WO-2000050093-A1 | METHOD OF MEASURING PHYSIOLOGICAL FUNCTION | MALLINCKRODT INC. (US) | 2000-08-31 | — | — | WO | claimed |
| EP-1154802-A1 | METHOD OF MEASURING PHYSIOLOGICAL FUNCTION | Mallinckrodt Inc. (US) | 2001-11-21 | — | — | EP | disclosed |
| WO-2000050093-A1 | METHOD OF MEASURING PHYSIOLOGICAL FUNCTION | MALLINCKRODT INC. (US) | 2000-08-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080167243-A1 | immunizing a subject with a sufficient amount of a translated polypeptide to produce antibody; containing a phenylalanine or tyrosine derivative analoges | DNPEP, NPEPPS, TYR | TSHR 1266/4885ALDH1A1 4657/4885CYP1A2 4625/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.