⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL843090 | 0.97 | — | — | |
| SCHEMBL8532748 | 0.78 | — | — | |
| SCHEMBL8534952 | 0.78 | — | — | |
| SCHEMBL3038207 | 0.71 | — | — | |
| SCHEMBL16439179 | 0.71 | — | — | |
| SCHEMBL15910483 | 0.70 | — | — | |
| SCHEMBL18775436 | 0.69 | LMNA (0.33) | — | |
| SCHEMBL17400860 | 0.69 | — | — | |
| SCHEMBL2558387 | 0.69 | — | — | |
| SCHEMBL4485232 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 152 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109988172-B | Synthesis method of pyrazolo [1,5-A ] pyrimidine heterocyclic compound and derivative | 石家庄学院 | 2020-09-29 | — | — | CN | claimed |
| EP-4710923-A2 | INDOLE AHR INHIBITORS AND USES THEREOF | Ikena Oncology, Inc. (US) | 2026-03-18 | — | — | EP | disclosed |
| US-RE50776-E1 | Inhibitors of cyclin-dependent kinases | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2026-02-03 | — | — | US | disclosed |
| EP-3612030-B1 | INDOLE AHR INHIBITORS AND USES THEREOF | IKENA ONCOLOGY INC (US) | 2025-12-24 | — | — | EP | disclosed |
| US-20250122205-A1 | INDOLE AHR INHIBITORS AND USES THEREOF | PAHR THERAPEUTICS, INC. | 2025-04-17 | — | — | US | disclosed |
| US-12098154-B2 | Inhibitors of cyclin-dependent kinases | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2024-09-24 | — | — | US | disclosed |
| US-12083121-B2 | Substituted piperazines as KRAS G12C inhibitors | AMGEN INC. (US) | 2024-09-10 | — | — | US | disclosed |
| US-12077542-B2 | Indole AHR inhibitors and uses thereof | Ikena Oncology, Inc. (US) | 2024-09-03 | — | — | US | disclosed |
| CN-114929345-B | Substituted pyrazole compounds as TOLL receptor inhibitors | 百时美施贵宝公司 | 2024-07-23 | — | — | CN | disclosed |
| CN-113004285-B | Heterocyclic compound, pharmaceutical composition, preparation method, intermediate and application thereof | 苏州信诺维医药科技股份有限公司 | 2024-05-14 | — | — | CN | disclosed |
| US-20100261683-A1 | Selective Inhibitors for Cyclin-Dependent Kinases | EMORY UNIVERSITY | 2010-10-14 | — | — | US | disclosed |
| WO-2010068838-A2 | PROCESSES FOR PREPARING 5,7 DIAMINOPYRAZOLO[1,5-α] PYRIMIDINE COMPOUNDS | EMORY UNIVERSITY (US) | 2010-06-17 | — | — | WO | disclosed |
| EP-2170073-A1 | SELECTIVE INHIBITORS FOR CYCLIN-DEPENDENT KINASES | Emory University (US) | 2010-04-07 | — | — | EP | disclosed |
| WO-2008151304-A1 | SELECTIVE INHIBITORS FOR CYCLIN-DEPENDENT KINASES | EMORY UNIVERSITY (US) | 2008-12-11 | — | — | WO | disclosed |
| WO-2008151304-A1 | SELECTIVE INHIBITORS FOR CYCLIN-DEPENDENT KINASES | EMORY UNIVERSITY (US) | 2008-12-11 | — | — | WO | disclosed |
| US-20070179161-A1 | Pyrazolopyrimidine compounds and their use in medicine | VERNALIS (CAMBRIDGE) LIMITED. (GB) | 2007-08-02 | — | — | US | disclosed |
| US-20070179161-A1 | Pyrazolopyrimidine compounds and their use in medicine | VERNALIS (CAMBRIDGE) LIMITED. (GB) | 2007-08-02 | — | — | US | disclosed |
| US-20070179161-A1 | Pyrazolopyrimidine compounds and their use in medicine | VERNALIS (CAMBRIDGE) LIMITED. (GB) | 2007-08-02 | — | — | US | disclosed |
| EP-1608652-A1 | PYRAZOLOPYRIMIDINE COMPOUNDS AND THEIR USE IN MEDICINE | Vernalis (Cambridge) Limited (GB) | 2005-12-28 | — | — | EP | disclosed |
| WO-2004087707-A1 | PYRAZOLOPYRIMIDINE COMPOUNDS AND THEIR USE IN MEDICINE | VERNALIS (CAMBRIDGE) LIMITED (GB) | 2004-10-14 | — | — | WO | disclosed |