⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15910483 | 0.98 | — | — | |
| SCHEMBL4075633 | 0.73 | THRB (0.31) | — | |
| Potassium SCHEMBL29519191 | 0.71 | — | — | |
| SCHEMBL4830005 | 0.71 | — | — | |
| SCHEMBL599404 | 0.69 | — | — | |
| SCHEMBL11882182 | 0.67 | — | — | |
| SCHEMBL843090 | 0.67 | — | — | |
| SCHEMBL8534952 | 0.65 | — | — | |
| SCHEMBL8532748 | 0.65 | — | — | |
| SCHEMBL18775436 | 0.62 | LMNA (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9896454-B2 | Microbiocidal heterobicyclic derivatives | SYNGENTA PARTICIPATIONS AG (CH) | 2018-02-20 | — | — | US | disclosed |
| EP-3114127-B1 | MICROBIOCIDAL HETEROBICYCLIC DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2017-11-29 | — | — | EP | disclosed |
| US-20170073346-A1 | MICROBIOCIDAL HETEROBICYCLIC DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2017-03-16 | — | — | US | disclosed |
| EP-3114127-A1 | MICROBIOCIDAL HETEROBICYCLIC DERIVATIVES | Syngenta Participations AG (CH) | 2017-01-11 | — | — | EP | disclosed |
| WO-2015132133-A1 | MICROBIOCIDAL HETEROBICYCLIC DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2015-09-11 | — | — | WO | disclosed |
| US-7615639-B2 | 1-pyridyl-benzofuro[3,2-b]pyridin-2(1H)-ones | TIBOTEC PHARMACEUTICALS, LTD. (IE) | 2009-11-10 | — | — | US | disclosed |
| US-20070265295-A1 | 1-Heterocyclyl-1,5-Dihydro-Pyrido[3,2-B]Indol-2-Ones | TIBOTEC PHARMACEUTICALS LTD. (IE) | 2007-11-15 | — | — | US | disclosed |
| EP-1758911-A1 | 1-HETEROCYCLYL-1,5-DIHYDRO-PYRIDO[3,2-B]INDOL-2-ONES | Tibotec Pharmaceuticals Ltd. (IE) | 2007-03-07 | — | — | EP | disclosed |
| WO-2005111047-A1 | 1-HETEROCYCLYL-1,5-DIHYDRO-PYRIDO[3,2-B]INDOL-2-ONES | TIBOTEC PHARMACEUTICALS LTD. (IE) | 2005-11-24 | — | — | WO | disclosed |