SCHEMBL5994253

SCHEMBL5994253

COc1ccc(C(=O)C(C)[P](=O)C(=O)c2c(C)cccc2C)c(OC)c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.46
NPC1 O15118 2/20 0.46
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
RAB9A P51151 1/20 0.46
ABCG2 Q9UNQ0 5/20 0.46
TNFRSF1A P19438 1/20 0.45
PDE4A P27815 1/20 0.44
PDE4B Q07343 1/20 0.44
PDE4C Q08493 1/20 0.44
PDE4D Q08499 1/20 0.44
TP53 P04637 1/20 0.44
XDH P47989 1/20 0.43
ALDH1A1 P00352 1/20 0.43
CYP1A1 P04798 1/20 0.41
CYP1A2 P05177 1/20 0.41
CYP3A4 P08684 1/20 0.41
CYP2D6 P10635 1/20 0.41
CYP1B1 Q16678 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5995294 0.90 TP53 (0.44) MAPTNPC1MEN1KMT2ARAB9A
SCHEMBL5994823 0.90 MAPT (0.47) MAPTNPC1MEN1KMT2ARAB9A
SCHEMBL6824914 0.87 PDE4A (0.48) MAPTNPC1MEN1KMT2ARAB9A
SCHEMBL5996138 0.87 PDE4A (0.42) MAPTNPC1MEN1KMT2ARAB9A
SCHEMBL5997937 0.86 ABCG2 (0.45) MAPTMEN1KMT2AABCG2TP53
SCHEMBL5996392 0.84 ABCG2 (0.45) MAPTMEN1KMT2AABCG2TP53
SCHEMBL5996726 0.81 TAS1R3 (0.38) MAPTKMT2AABCG2TP53ALDH1A1
SCHEMBL5995539 0.79 CA12 (0.44) MAPTKMT2AALDH1A1L3MBTL1
SCHEMBL5994346 0.76 ABCG2 (0.46) MAPTKMT2AABCG2TP53CYP3A4
SCHEMBL6397140 0.74 CYP3A4 (0.40) MAPTMEN1KMT2AABCG2TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7026017-B2 Photoinitiators for acrylic esters; reacting an acyl halide with a metal benzoyl phosphine; cable coatings, screen printing stencils, resist materials, colour filters, electrical encapsulation CIBA SPECIALTY CHEMICALS CORPORATION (US) 2006-04-11 US disclosed
US-6737549-B2 PHOTOINITIATORS FOR ACRYLATE COATINGS CIBA SPECIALTY CHEMICALS CORPORATION 2004-05-18 US disclosed
US-20030130370-A1 Photoinitiators for acrylic esters; reacting an acyl halide with a metal benzoyl phosphine; cable coatings, screen printing stencils, resist materials, colour filters, electrical encapsulation WOLF JEAN-PIERRE (CH) 2003-07-10 US disclosed
US-20020026049-A1 Photoinitiators for acrylate coatings CIBA SPECIALTY CHEMICALS CORP. 2002-02-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030130370-A1 Photoinitiators for acrylic esters; reacting an acyl halide with a metal benzoyl phosphine; cable coatings, screen printing stencils, resist materials, colour filters, electrical encapsulation SMARCC1, ARPC5L, DHCR24 MAPT 4813/4885NPC1 1321/4885MEN1 2456/4885
US-20020026049-A1 Photoinitiators for acrylate coatings DHCR24, NR5A1, NR2C2 MAPT 4467/4885NPC1 623/4885MEN1 3695/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.