SCHEMBL5994368

SCHEMBL5994368

C=CC(=O)OC(CO)(OC(=O)C=C)OC(=O)C=C

nearest known ligand 0.50

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.50
TP53 P04637 3/20 0.50
HIF1A Q16665 3/20 0.50
CYP3A4 P08684 2/20 0.50
MAPK1 P28482 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
TSHR P16473 6/20 0.44
HSD17B10 Q99714 1/20 0.39
HPGD P15428 1/20 0.35
THRB P10828 1/20 0.33
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Mellitic Acid SCHEMBL7107225 0.88 ALDH1A1 (0.41) ALDH1A1TP53HIF1ACYP3A4MAPK1
SCHEMBL29368939 0.82 ALDH1A1 (0.53) ALDH1A1TP53HIF1ACYP3A4MAPK1
SCHEMBL27949807 0.80 ALDH1A1 (0.40) ALDH1A1TP53HIF1ACYP3A4MAPK1
SCHEMBL31563674 0.80 ALDH1A1 (0.50) ALDH1A1TP53HIF1ACYP3A4MAPK1
SCHEMBL27551478 0.80 ALDH1A1 (0.50) ALDH1A1TP53HIF1ACYP3A4MAPK1
SCHEMBL3747050 0.80 ALDH1A1 (0.50) ALDH1A1TP53HIF1ACYP3A4MAPK1
SCHEMBL17961076 0.78 ALDH1A1 (0.48) ALDH1A1TP53HIF1ACYP3A4MAPK1
SCHEMBL1706295 0.78 THRB (0.44) ALDH1A1TP53HIF1ACYP3A4MAPK1
SCHEMBL2530173 0.78 TSHR (0.43) ALDH1A1TP53HIF1ACYP3A4MAPK1
SCHEMBL2928258 0.76 ALDH1A1 (0.57) ALDH1A1TP53HIF1ACYP3A4MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106748026-A A kind of corn Special wooden element slow-release or control-release fertilizer 浙江农林大学 2017-05-31 CN claimed
CN-104817998-A Solid-solid phase change energy storage hydrogel with stable shape and preparation method thereof UNIV SOUTHEAST 2015-08-05 CN claimed
CN-103013014-B Super-strong hydrogel with plurality of networks and preparation method thereof UNIV SOUTHEAST 2014-12-17 CN claimed
CN-106748026-A A kind of corn Special wooden element slow-release or control-release fertilizer 浙江农林大学 2017-05-31 CN disclosed
CN-104817998-A Solid-solid phase change energy storage hydrogel with stable shape and preparation method thereof UNIV SOUTHEAST 2015-08-05 CN disclosed
US-7012057-B2 Detergent bars comprising radiation curable resins UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. (US) 2006-03-14 US disclosed
EP-1448758-B1 IMPROVEMENTS RELATING TO DETERGENT BARS UNILEVER NV (NL) 2005-04-20 EP disclosed
US-20050014666-A1 Detergent bars UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. 2005-01-20 US disclosed
EP-1448758-A1 IMPROVEMENTS RELATING TO DETERGENT BARS UNILEVER N.V. (NL) 2004-08-25 EP disclosed
WO-2003046119-A1 IMPROVEMENTS RELATING TO DETERGENT BARS UNILEVER N.V. (NL) 2003-06-05 WO disclosed