SCHEMBL599442

SCHEMBL599442

CC1(C)CC(CCCCNc2ncnc(NCCCCC3CC(C)(C)N(OC4CCCCC4)C(C)(C)C3)n2)CC(C)(C)N1OC1CCCCC1

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TNKS2 Q9H2K2 1/20 0.31
SIGMAR1 Q99720 1/20 0.30
HRH4 Q9H3N8 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8653406 0.93
SCHEMBL1231055 0.92 TNKS2 (0.34) TNKS2SIGMAR1
SCHEMBL5555137 0.91 TNKS2 (0.31) TNKS2SIGMAR1
SCHEMBL452494 0.87 KMT2A (0.36) TNKS2SIGMAR1
SCHEMBL9428266 0.87 TLR7 (0.36) TNKS2SIGMAR1
SCHEMBL526852 0.87 KMT2A (0.36) TNKS2
SCHEMBL9428455 0.86 KMT2A (0.38) TNKS2SIGMAR1
SCHEMBL9428448 0.86 KMT2A (0.38) TNKS2SIGMAR1
SCHEMBL9428473 0.86 TLR7 (0.35) TNKS2SIGMAR1
SCHEMBL9429087 0.86 KMT2A (0.38) TNKS2SIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10072128-B2 Polyolefin-based resin pre-expanded particles and polyolefin-based resin in-mold expansion molded article comprising polyolefin-based resin pre- expanded particles KANEKA CORPORATION (JP) 2018-09-11 US disclosed
EP-2743295-B1 POLYOLEFIN RESIN FOAM PARTICLES AND IN-MOLD FOAMING MOLDED BODY OF SAME KANEKA CORP (JP) 2016-04-27 EP disclosed
US-9249281-B2 Polyolefin resin foam particles and in-mold foaming molded body of same KANEKA CORPORATION (JP) 2016-02-02 US disclosed
US-20150210815-A1 POLYOLEFIN-BASED RESIN PRE-EXPANDED PARTICLES AND POLYOLEFIN-BASED RESIN IN-MOLD EXPANSION MOLDED ARTICLE COMPRISING POLYOLEFIN-BASED RESIN PRE-EXPANDED PARTICLES KANEKA CORPORATION (JP) 2015-07-30 US disclosed
EP-2420533-B1 POLYOLEFIN RESIN PRE-EXPANDED PARTICLES AND POLYOLEFIN RESIN IN-MOLD EXPANSION-MOLDED ARTICLE COMPRISING POLYOLEFIN RESIN PRE-EXPANDED PARTICLES KANEKA CORP (JP) 2014-12-31 EP disclosed
US-20140171534-A1 POLYOLEFIN RESIN FOAM PARTICLES AND IN-MOLD FOAMING MOLDED BODY OF SAME KANEKA CORPORATION (JP) 2014-06-19 US disclosed
EP-2743295-A1 POLYOLEFIN RESIN FOAM PARTICLES AND IN-MOLD FOAMING MOLDED BODY OF SAME Kaneka Corporation (JP) 2014-06-18 EP disclosed
EP-2420533-A1 POLYOLEFIN RESIN PRE-EXPANDED PARTICLES AND POLYOLEFIN RESIN IN-MOLD EXPANSION-MOLDED ARTICLE COMPRISING POLYOLEFIN RESIN PRE-EXPANDED PARTICLES Kaneka Corporation (JP) 2012-02-22 EP disclosed
US-20120037837-A1 POLYOLEFIN-BASED RESIN PRE-EXPANDED PARTICLES AND POLYOLEFIN-BASED RESIN IN-MOLD EXPANSION MOLDED ARTICLE COMPRISING POLYOLEFIN-BASED RESIN PRE-EXPANDED PARTICLES KANEKA CORPORATION (JP) 2012-02-16 US disclosed
EP-1454947-B1 FLAME RETARDANT POLYOLEFIN RESIN PRE-EXPANDED PARTICLES AND IN-MOLD FOAMED ARTICLES PREPARED THEREFROM KANEKA CORP (JP) 2010-02-17 EP disclosed
US-6822023-B2 MIXTURE CONTAINING STERIC HINDERED OXYAMINE COMPOUND KANEKA CORPORATION (JP) 2004-11-23 US disclosed
EP-1454947-A1 PRE−EXPANDED BEADS OF FLAME−RETARDANT POLYOLEFIN RESIN AND MOLDED OBJECT THEREOF BY IN−MOLD FOAMING KANEKA CORPORATION (JP) 2004-09-08 EP disclosed
US-20030105194-A1 Flame retardant polyolefin resin pre-expanded particles and in-mold foamed articles prepared therefrom KANEKA CORPORATION (JP) 2003-06-05 US disclosed