SCHEMBL452494

SCHEMBL452494

CC1(C)CC(CCCCNc2nc(Cl)nc(NCCCCC3CC(C)(C)N(OC4CCCCC4)C(C)(C)C3)n2)CC(C)(C)N1OC1CCCCC1

nearest known ligand 0.38

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.36
PDE4A P27815 2/20 0.32
TNKS2 Q9H2K2 1/20 0.31
SIGMAR1 Q99720 1/20 0.30
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9428448 0.99 KMT2A (0.38) KMT2APDE4ATNKS2SIGMAR1
SCHEMBL9429087 0.99 KMT2A (0.38) KMT2APDE4ATNKS2SIGMAR1
SCHEMBL524341 0.98 KMT2A (0.33) KMT2ATNKS2SIGMAR1
SCHEMBL1231055 0.94 TNKS2 (0.34) TNKS2SIGMAR1
SCHEMBL9428266 0.89 TLR7 (0.36) TNKS2SIGMAR1
SCHEMBL526852 0.89 KMT2A (0.36) KMT2ATNKS2
SCHEMBL8653406 0.89
SCHEMBL9428455 0.88 KMT2A (0.38) KMT2ATNKS2SIGMAR1
SCHEMBL9428473 0.88 TLR7 (0.35) KMT2ATNKS2SIGMAR1
SCHEMBL9428560 0.88 KMT2A (0.38) KMT2ATNKS2SIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 236 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024053584-A1 POLYPROPYLENE-BASED FOAM PARTICLES, POLYPROPYLENE-BASED FOAM MOLDED BODY, AND METHODS FOR PRODUCING SAME 株式会社カネカ 2024-03-14 WO claimed
WO-2023090311-A1 POLYPROPYLENE FOAM PARTICLES AND POLYPROPYLENE FOAM MOLDED BODY, AND METHODS FOR PRODUCING SAME 株式会社カネカ 2023-05-25 WO claimed
US-20230072612-A1 FLAME RETARDANT CHEMICAL COMPOSITIONS NORDTREAT FINLAND OY (FI) 2023-03-09 US claimed
CN-115087697-A Flame retardant chemical composition 诺德特利特芬兰公司 2022-09-20 CN claimed
US-10414985-B2 Heptaphosphorus-derived compounds as flame retardants BASF SE (DE) 2019-09-17 US claimed
US-20180216008-A1 HEPTAPHOSPHORUS-DERIVED COMPOUNDS AS FLAME RETARDANTS BASF SE (DE) 2018-08-02 US claimed
EP-3122813-B1 HEPTAPHOSPHORUS-DERIVED COMPOUNDS AS FLAME RETARDANTS BASF SE (DE) 2018-03-07 EP claimed
EP-3122813-A2 HEPTAPHOSPHORUS-DERIVED COMPOUNDS AS FLAME RETARDANTS BASF SE (DE) 2017-02-01 EP claimed
EP-2464739-B1 METHODS IN CELL CULTURES, AND RELATED INVENTIONS, EMPLOYING CERTAIN ADDITIVES BASF SE (DE) 2016-01-13 EP claimed
WO-2015144667-A2 HEPTAPHOSPHORUS-DERIVED COMPOUNDS AS FLAME RETARDANTS BASF SE (DE) 2015-10-01 WO claimed
WO-2005014706-A1 FLAME RETARDANT POLYLACTIC ACID CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2005-02-17 WO claimed
US-20050014948-A1 Hydrogen peroxide catalyzed process for the preparation of sterically hindered N-hydrocarbyloxyamines CIBA SPECIALTY CHEMICALS CORP. 2005-01-20 US claimed
US-20050014871-A1 Flame retardant polylactic acid CIBA SPECIALTY CHEMICALS CORP. 2005-01-20 US claimed
WO-2005005388-A1 HYDROGEN PEROXIDE CATALYZED PROCESS FOR THE PREPARATION OF STERICALLY HINDERED N-HYDROCARBYLOXYAMINES CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2005-01-20 WO claimed
US-20040138351-A1 Flame retardant compositions CIBA SPECIALTY CHEMICALS CORP. 2004-07-15 US claimed
US-20040116565-A1 Flame retardant compositions CIBA SPECIALTY CHEMICALS CORP. 2004-06-17 US claimed
WO-2004041919-A2 FLAME RETARDANT COMPOSITIONS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2004-05-21 WO claimed
US-20040097620-A1 Flame retardant compositions CIBA SPECIALTY CHEMICALS CORP. 2004-05-20 US claimed
US-20040087689-A1 Flame retardant polymeric electrical parts CIBA SPECIALTY CHEMICALS CORP. 2004-05-06 US claimed
WO-2004035671-A1 FLAME RETARDANT COMPOSITIONS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2004-04-29 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180216008-A1 HEPTAPHOSPHORUS-DERIVED COMPOUNDS AS FLAME RETARDANTS PFAS, PCBP1, DDT KMT2A 1171/4885PDE4A 4259/4885TNKS2 1832/4885
US-20050014948-A1 Hydrogen peroxide catalyzed process for the preparation of sterically hindered N-hydrocarbyloxyamines HAO2, SOD1, PPOX KMT2A 924/4885PDE4A 4382/4885TNKS2 3298/4885
US-10414985-B2 Heptaphosphorus-derived compounds as flame retardants PFAS, PCBP1, DDT KMT2A 1058/4885PDE4A 4500/4885TNKS2 1657/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.