SCHEMBL9428455

SCHEMBL9428455

CC1(C)CC(CCCCCCCCCCCCNc2nc(NCCO)nc(NCCCCCCCCCCCCC3CC(C)(C)N(OC4CCCCC4)C(C)(C)C3)n2)CC(C)(C)N1OC1CCCCC1

nearest known ligand 0.38

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.38
CDK1 P06493 3/20 0.34
CDK2 P24941 2/20 0.34
CCNB2 O95067 1/20 0.34
CCNB1 P14635 1/20 0.34
CCNA2 P20248 1/20 0.34
CCNA1 P78396 1/20 0.34
CCNB3 Q8WWL7 1/20 0.34
SLC29A1 Q99808 4/20 0.33
SIGMAR1 Q99720 1/20 0.32
GBA1 P04062 5/20 0.32
NAAA Q02083 1/20 0.31
ALDH1A1 P00352 1/20 0.31
TNKS2 Q9H2K2 1/20 0.31
EHMT2 Q96KQ7 1/20 0.31
EHMT1 Q9H9B1 1/20 0.31
POLB P06746 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9428560 1.00 KMT2A (0.38) KMT2ACDK1CDK2CCNB2CCNB1
SCHEMBL526852 0.99 KMT2A (0.36) KMT2ACDK1CDK2CCNB2CCNB1
SCHEMBL1231055 0.93 TNKS2 (0.34) SIGMAR1NAAATNKS2
SCHEMBL9428448 0.89 KMT2A (0.38) KMT2ASIGMAR1TNKS2
SCHEMBL9429087 0.89 KMT2A (0.38) KMT2ASIGMAR1TNKS2
SCHEMBL9428473 0.89 TLR7 (0.35) KMT2ASIGMAR1TNKS2
SCHEMBL9428181 0.89 CDK1 (0.31) KMT2ACDK1
SCHEMBL9428298 0.88 CTSS (0.32) SIGMAR1ALDH1A1TNKS2
SCHEMBL452494 0.88 KMT2A (0.36) KMT2ASIGMAR1TNKS2
SCHEMBL9428266 0.88 TLR7 (0.36) SIGMAR1TNKS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5300544-A Non-migrating 1-hydrocarbyloxy-2,2,6,6-tetramethylpiperdine 1,3,5-triazine derivatives as polymer stabilizers CIBA-GEIGY CORPORATION (US) 1994-04-05 US disclosed
US-5216156-A Stabilizers having functional groups which chemically bond with polymer substrates CIBA-GEIGY CORPORATION (US) 1993-06-01 US disclosed