SCHEMBL5994583

SCHEMBL5994583

CCP(=O)(C(=O)c1c(C)cc(C)cc1C)C(=O)c1c(OC)cc(OC)cc1OC

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 4/20 0.42
SMN1; SMN2 Q16637 3/20 0.42
USP2 O75604 1/20 0.42
MAPK1 P28482 1/20 0.42
HPGD P15428 3/20 0.41
KMT2A Q03164 3/20 0.39
ABCG2 Q9UNQ0 2/20 0.38
CYP2D6 P10635 2/20 0.37
CYP2C19 P33261 1/20 0.37
LMNA P02545 3/20 0.36
HTR1A P08908 1/20 0.36
ADRA2A P08913 1/20 0.36
ADRA2C P18825 1/20 0.36
OPRK1 P41145 1/20 0.36
KCNH2 Q12809 1/20 0.36
EBP Q15125 1/20 0.36
SIGMAR1 Q99720 1/20 0.36
HRH3 Q9Y5N1 1/20 0.36
PKM P14618 1/20 0.36
MEN1 O00255 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5994796 0.94 PKM (0.38) CYP3A4SMN1; SMN2USP2MAPK1HPGD
SCHEMBL5993728 0.88 ELANE (0.38) CYP3A4SMN1; SMN2USP2MAPK1HPGD
SCHEMBL5996227 0.88 CYP3A4 (0.39) CYP3A4SMN1; SMN2USP2MAPK1HPGD
SCHEMBL5996374 0.87 TAS1R3 (0.44) CYP3A4SMN1; SMN2USP2MAPK1KMT2A
SCHEMBL5997081 0.87 TAS1R3 (0.44) CYP3A4SMN1; SMN2MAPK1KMT2ACYP2C19
SCHEMBL5995481 0.87 CYP3A4 (0.38) CYP3A4SMN1; SMN2USP2MAPK1HPGD
SCHEMBL5995274 0.85 HDAC3 (0.45) SMN1; SMN2HPGDKMT2AABCG2LMNA
SCHEMBL5996043 0.85 CNR2 (0.37) SMN1; SMN2HPGDLMNAPKMRAB9A
SCHEMBL2499305 0.84 HPGD (0.45) SMN1; SMN2MAPK1HPGDKMT2ALMNA
SCHEMBL5996716 0.84 TAS1R3 (0.44) CYP3A4MAPK1KMT2ACYP2C19PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7026017-B2 Photoinitiators for acrylic esters; reacting an acyl halide with a metal benzoyl phosphine; cable coatings, screen printing stencils, resist materials, colour filters, electrical encapsulation CIBA SPECIALTY CHEMICALS CORPORATION (US) 2006-04-11 US disclosed
US-6969733-B2 Photoinitiators CIBA SPECIALTY CHEMICALS CORPORATION (US) 2005-11-29 US disclosed
US-6737549-B2 PHOTOINITIATORS FOR ACRYLATE COATINGS CIBA SPECIALTY CHEMICALS CORPORATION 2004-05-18 US disclosed
US-20030139485-A1 Photoinitiators WOLF JEAN-PIERRE (CH) 2003-07-24 US disclosed
US-20030130370-A1 Photoinitiators for acrylic esters; reacting an acyl halide with a metal benzoyl phosphine; cable coatings, screen printing stencils, resist materials, colour filters, electrical encapsulation WOLF JEAN-PIERRE (CH) 2003-07-10 US disclosed
US-20020026049-A1 Photoinitiators for acrylate coatings CIBA SPECIALTY CHEMICALS CORP. 2002-02-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030139485-A1 Photoinitiators DHCR24, NR1I3, CBR1 CYP3A4 432/4885SMN1; SMN2 3940/4885USP2 4345/4885
US-20030130370-A1 Photoinitiators for acrylic esters; reacting an acyl halide with a metal benzoyl phosphine; cable coatings, screen printing stencils, resist materials, colour filters, electrical encapsulation SMARCC1, ARPC5L, DHCR24 CYP3A4 2973/4885SMN1; SMN2 1663/4885USP2 4183/4885
US-20020026049-A1 Photoinitiators for acrylate coatings DHCR24, NR5A1, NR2C2 CYP3A4 946/4885SMN1; SMN2 4099/4885USP2 3795/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.