Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | GALR3 | O60755 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 7/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.34 |
| ▸ | ALB | P02768 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | WDR5 | P61964 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7248979 | 1.00 | RAB9A (0.39) | RAB9AGALR3MAPTGAARXFP1 | |
| SCHEMBL5995047 | 1.00 | RAB9A (0.39) | RAB9AGALR3MAPTGAARXFP1 | |
| SCHEMBL30166490 | 1.00 | RAB9A (0.39) | RAB9AGALR3MAPTGAARXFP1 | |
| SCHEMBL6691478 | 0.81 | NR1I2 (0.41) | NR1I2ALBPDE4D | |
| SCHEMBL6691481 | 0.81 | NR1I2 (0.41) | NR1I2ALBPDE4D | |
| SCHEMBL332026 | 0.81 | NR1I2 (0.41) | NR1I2ALBPDE4D | |
| SCHEMBL13790123 | 0.81 | NR1I2 (0.41) | NR1I2ALBPDE4D | |
| SCHEMBL18480735 | 0.79 | NR1I2 (0.33) | NR1I2ALBPDE4D | |
| SCHEMBL6322977 | 0.79 | — | — | |
| SCHEMBL20616297 | 0.77 | NR1I2 (0.32) | NR1I2ALBPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7115590-B1 | Phosphoramidate, and mono-, di-, and tri-phosphate esters of (1R, cis)-4-(6-amino-9H-purin-9-yl)-2-cyclopentene-1-methanol as antiviral agents | UNIVERSITY COLLEGE CARDIFF CONSULTANTS LIMITED (GB) | 2006-10-03 | — | — | US | disclosed |
| US-6630477-B1 | Therapeutic nucleoside compound | SMITHKLINE BEECHAM CORPORATION | 2003-10-07 | — | — | US | disclosed |
| EP-1150988-B1 | PHOSPHORAMIDATE, AND MONO-, DI-, AND TRI-PHOSPHATE ESTERS OF (1R, CIS)-4-(6-AMINO-9H-PURIN-9-YL)-2-CYCLOPENTENE-1-METHANOL AS ANTIVIRAL AGENTS | GLAXO GROUP LTD (GB) | 2003-05-28 | — | — | EP | disclosed |
| US-6534512-B1 | A therapeutic method is provided, employing an antiviral compound of the general formula: nucleosides which exhibit antiviral activity. | REGENTS OF THE UNIVERSITY OF MINNESOTA | 2003-03-18 | — | — | US | disclosed |
| US-6072053-A | ANTIVIRAL COMPOUND | UNIV MINNESOTA (US) | 2000-06-06 | — | — | US | disclosed |
| US-5962684-A | Method of preparation of dideoxycarbocyclic nucleosides | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 1999-10-05 | — | — | US | disclosed |
| US-5922694-A | SUBSTITUTED-OXY METHYL CYCLOPENTENYL-SUBSTITUTED PURINES AND 8-AZAPURINES ANTI HUMAN IMMUNODEFICIENCY VIRUS | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 1999-07-13 | — | — | US | disclosed |
| US-5763607-A | VIRICIDES | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 1998-06-09 | — | — | US | disclosed |
| US-5631370-A | VIRICIDES FOR HUMAN T-CELL LEUKEMIA/LYMPHOMA | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 1997-05-20 | — | — | US | disclosed |
| US-5175292-A | Viricides, aids | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 1992-12-29 | — | — | US | disclosed |
| US-5122517-A | Human t-cell leukemia/lymphoma viruses | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 1992-06-16 | — | — | US | disclosed |
| EP-0346132-B1 | PHARMACEUTICAL PRODUCTS | THE REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 1992-03-11 | — | — | EP | disclosed |
| US-4950758-A | ANTIVIRAL AND ANTITUMOR AGENTS | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 1990-08-21 | — | — | US | disclosed |
| US-4931559-A | VIRICIDES, ANTITUMOR AGENTS | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 1990-06-05 | — | — | US | disclosed |
| US-4916224-A | VIRICIDES FOR TREATING HUMAN IMMUNODEFICIENCY VIRUS INFECTION | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 1990-04-10 | — | — | US | disclosed |
| EP-0346132-A1 | Pharmaceutical products | THE REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 1989-12-13 | — | — | EP | disclosed |