Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | KIF11 | P52732 | 1/20 | 0.36 |
| ▸ | KCNN4 | O15554 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL173485 | 0.78 | KMT2A (0.44) | MAPTKMT2ANR3C2HTTKIF11 | |
| SCHEMBL5674843 | 0.76 | MAPT (0.52) | MAPTKMT2ANR3C2HTTKCNN4 | |
| SCHEMBL27942173 | 0.75 | ALDH1A1 (0.39) | KMT2ANR3C2HTTKCNN4PTGS2 | |
| SCHEMBL877679 | 0.73 | ALDH1A1 (0.35) | MAPTPTGS2 | |
| SCHEMBL18112741 | 0.72 | KMT2A (0.43) | MAPTKMT2AHTTKIF11KCNN4 | |
| SCHEMBL8707463 | 0.72 | CYP2C19 (0.48) | MAPTKMT2ANR3C2HTTCYP2C19 | |
| SCHEMBL9998615 | 0.72 | MAPT (0.38) | MAPTKMT2ANR3C2HTTKCNN4 | |
| SCHEMBL878148 | 0.72 | ALDH1A1 (0.38) | HTTKIF11LMNAPTGS2CHRM2 | |
| SCHEMBL4943741 | 0.71 | CYP1A2 (0.46) | MAPTKMT2AHTTKIF11KCNN4 | |
| SCHEMBL877681 | 0.70 | CYP2C19 (0.37) | KMT2ANR3C2HTTKCNN4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060205980-A1 | Substituted N-sulfonylaminophenylethyl-2-phenoxyacetamide compounds as VR1 receptor antagonists | PFIZER, INC. | 2006-09-14 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060205980-A1 | Substituted N-sulfonylaminophenylethyl-2-phenoxyacetamide compounds as VR1 receptor antagonists | CNR1, HVCN1, AVPR1A | MAPT 4726/4885KMT2A 2669/4885NR3C2 562/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.