Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 3/20 | 0.54 |
| ▸ | MET | P08581 | 14/20 | 0.53 |
| ▸ | KDR | P35968 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5997190 | 0.91 | SRC (0.56) | SRCMETKDR | |
| SCHEMBL2498345 | 0.90 | GAA (0.52) | SRCMET | |
| SCHEMBL2494861 | 0.87 | MET (0.46) | SRCMET | |
| SCHEMBL2497853 | 0.87 | BTK (0.51) | SRCMETKDR | |
| SCHEMBL5998263 | 0.86 | LCK (0.55) | SRCMETKDR | |
| SCHEMBL5997396 | 0.84 | SRC (0.58) | SRCKDR | |
| SCHEMBL14304877 | 0.84 | BTK (0.52) | SRCMETKDR | |
| SCHEMBL2500715 | 0.83 | BTK (0.68) | SRCKDR | |
| SCHEMBL5995311 | 0.81 | SRC (0.54) | SRCMETKDR | |
| SCHEMBL2494902 | 0.80 | BTK (0.56) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060247250-A1 | Pyrimidine inhibitors of kinases | TARGEGEN, INC. (US) | 2006-11-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060247250-A1 | Pyrimidine inhibitors of kinases | DTYMK, SRC, DCK | SRC 2/4885MET 2161/4885KDR 348/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.