SCHEMBL5996367

SCHEMBL5996367

CCCCP(=O)(C(=O)c1c(C)cccc1C)C(=O)c1c(Cl)cc(Cl)cc1Cl

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.36
HPGD P15428 2/20 0.36
F2R P25116 1/20 0.36
TYK2 P29597 1/20 0.34
SCN5A Q14524 3/20 0.34
SCN9A Q15858 3/20 0.34
ALOX12 P18054 1/20 0.33
POLB P06746 1/20 0.33
THRB P10828 1/20 0.33
RECQL P46063 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
TSHR P16473 1/20 0.33
CNR2 P34972 1/20 0.33
UTS2R Q9UKP6 1/20 0.33
EPHX2 P34913 1/20 0.33
MRGPRX4 Q96LA9 1/20 0.33
EPHX1 P07099 3/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
ITGB1 P05556 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5994155 0.91 TYK2 (0.42) ALDH1A1HPGDF2RTYK2TSHR
SCHEMBL5996814 0.88 HPGD (0.40) ALDH1A1HPGDALOX12POLBTHRB
SCHEMBL6467225 0.87 TSHR (0.41) ALDH1A1F2RL3MBTL1TSHRSMN1; SMN2
SCHEMBL5996312 0.86 TYK2 (0.37) ALDH1A1HPGDF2RTYK2ALOX12
SCHEMBL5996830 0.85 NR5A2 (0.33) ALDH1A1HPGDALOX12POLBTHRB
SCHEMBL5995028 0.84 MEN1 (0.40) HPGDF2RTYK2POLBTSHR
SCHEMBL5995827 0.84 PPARA (0.41) TSHRSMN1; SMN2ITGB1ITGA4
SCHEMBL5994658 0.83 SMN1; SMN2 (0.39) HPGDF2RPOLBL3MBTL1TSHR
SCHEMBL6470382 0.83 CETP (0.42) ALDH1A1F2RL3MBTL1TSHR
SCHEMBL6465547 0.82 CETP (0.44) ALDH1A1F2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7026017-B2 Photoinitiators for acrylic esters; reacting an acyl halide with a metal benzoyl phosphine; cable coatings, screen printing stencils, resist materials, colour filters, electrical encapsulation CIBA SPECIALTY CHEMICALS CORPORATION (US) 2006-04-11 US disclosed
US-6969733-B2 Photoinitiators CIBA SPECIALTY CHEMICALS CORPORATION (US) 2005-11-29 US disclosed
US-6737549-B2 PHOTOINITIATORS FOR ACRYLATE COATINGS CIBA SPECIALTY CHEMICALS CORPORATION 2004-05-18 US disclosed
US-20030139485-A1 Photoinitiators WOLF JEAN-PIERRE (CH) 2003-07-24 US disclosed
US-20030130370-A1 Photoinitiators for acrylic esters; reacting an acyl halide with a metal benzoyl phosphine; cable coatings, screen printing stencils, resist materials, colour filters, electrical encapsulation WOLF JEAN-PIERRE (CH) 2003-07-10 US disclosed
US-20020026049-A1 Photoinitiators for acrylate coatings CIBA SPECIALTY CHEMICALS CORP. 2002-02-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030139485-A1 Photoinitiators DHCR24, NR1I3, CBR1 ALDH1A1 974/4885HPGD 2368/4885F2R 4005/4885
US-20030130370-A1 Photoinitiators for acrylic esters; reacting an acyl halide with a metal benzoyl phosphine; cable coatings, screen printing stencils, resist materials, colour filters, electrical encapsulation SMARCC1, ARPC5L, DHCR24 ALDH1A1 1088/4885HPGD 3137/4885F2R 4529/4885
US-20020026049-A1 Photoinitiators for acrylate coatings DHCR24, NR5A1, NR2C2 ALDH1A1 835/4885HPGD 3884/4885F2R 3687/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.