SCHEMBL5996830

SCHEMBL5996830

CCCCP(=O)(C(=O)c1c(C)cc(C(C)(C)C)cc1C)C(=O)c1c(Cl)cc(Cl)cc1Cl

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR5A2 O00482 1/20 0.33
NR5A1 Q13285 1/20 0.33
ALDH1A1 P00352 3/20 0.32
ALOX12 P18054 1/20 0.32
FLT1 P17948 1/20 0.32
FLT4 P35916 1/20 0.32
KDR P35968 1/20 0.32
POLB P06746 2/20 0.32
THRB P10828 2/20 0.32
ACLY P53396 1/20 0.32
RECQL P46063 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
HDAC3 O15379 2/20 0.32
HDAC1 Q13547 2/20 0.32
HDAC2 Q92769 2/20 0.32
HDAC8 Q9BY41 1/20 0.32
HDAC6 Q9UBN7 1/20 0.32
LMNA P02545 1/20 0.31
CRHBP P24387 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5994829 0.89 NR5A2 (0.39) NR5A2NR5A1ALDH1A1POLBHDAC3
SCHEMBL5994505 0.89 RAB9A (0.38) NR5A2NR5A1ALDH1A1L3MBTL1HDAC3
SCHEMBL5996814 0.88 HPGD (0.40) ALDH1A1ALOX12POLBTHRBRECQL
SCHEMBL5995866 0.87 ACLY (0.35) FLT1FLT4KDRPOLBTHRB
SCHEMBL5995660 0.85 NR5A2 (0.36) NR5A2NR5A1ALDH1A1POLBL3MBTL1
SCHEMBL5996367 0.85 ALDH1A1 (0.36) ALDH1A1ALOX12POLBTHRBRECQL
SCHEMBL5995713 0.83 CNR1 (0.37) NR5A2NR5A1ALDH1A1THRBHDAC3
SCHEMBL5993904 0.81 FLT1 (0.33) ALDH1A1ALOX12FLT1FLT4KDR
SCHEMBL5995560 0.80 TSHR (0.35) NR5A2NR5A1ALDH1A1POLBHDAC3
SCHEMBL5993913 0.78 CNR2 (0.34) NR5A2NR5A1ALDH1A1POLBTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7026017-B2 Photoinitiators for acrylic esters; reacting an acyl halide with a metal benzoyl phosphine; cable coatings, screen printing stencils, resist materials, colour filters, electrical encapsulation CIBA SPECIALTY CHEMICALS CORPORATION (US) 2006-04-11 US disclosed
US-6969733-B2 Photoinitiators CIBA SPECIALTY CHEMICALS CORPORATION (US) 2005-11-29 US disclosed
US-6737549-B2 PHOTOINITIATORS FOR ACRYLATE COATINGS CIBA SPECIALTY CHEMICALS CORPORATION 2004-05-18 US disclosed
US-20030139485-A1 Photoinitiators WOLF JEAN-PIERRE (CH) 2003-07-24 US disclosed
US-20030130370-A1 Photoinitiators for acrylic esters; reacting an acyl halide with a metal benzoyl phosphine; cable coatings, screen printing stencils, resist materials, colour filters, electrical encapsulation WOLF JEAN-PIERRE (CH) 2003-07-10 US disclosed
US-20020026049-A1 Photoinitiators for acrylate coatings CIBA SPECIALTY CHEMICALS CORP. 2002-02-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030139485-A1 Photoinitiators DHCR24, NR1I3, CBR1 NR5A2 15/4885NR5A1 10/4885ALDH1A1 974/4885
US-20030130370-A1 Photoinitiators for acrylic esters; reacting an acyl halide with a metal benzoyl phosphine; cable coatings, screen printing stencils, resist materials, colour filters, electrical encapsulation SMARCC1, ARPC5L, DHCR24 NR5A2 25/4885NR5A1 176/4885ALDH1A1 1088/4885
US-20020026049-A1 Photoinitiators for acrylate coatings DHCR24, NR5A1, NR2C2 NR5A2 8/4885NR5A1 2/4885ALDH1A1 835/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.