SCHEMBL5996916

SCHEMBL5996916

CCCCPC(=O)c1c(C)cccc1Cl

nearest known ligand 0.40

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TYK2 P29597 1/20 0.40
FABP3 P05413 1/20 0.38
FABP4 P15090 1/20 0.38
ALDH1A1 P00352 2/20 0.38
HPGD P15428 2/20 0.37
TRPM4 Q8TD43 1/20 0.37
DRD3 P35462 1/20 0.37
UTS2R Q9UKP6 1/20 0.36
PLK1 P53350 1/20 0.36
HTT P42858 1/20 0.35
ITGB1 P05556 4/20 0.35
ITGA4 P13612 4/20 0.35
ITGA2 P17301 1/20 0.35
ITGB7 P26010 1/20 0.35
FEN1 P39748 1/20 0.35
LMNA P02545 1/20 0.35
POLB P06746 1/20 0.35
F2R P25116 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5997453 0.92 ALDH1A1 (0.44) ALDH1A1HPGDDRD3PLK1HTT
SCHEMBL5998257 0.89 F2R (0.38) ALDH1A1HTTF2R
SCHEMBL5997940 0.84 TYK2 (0.44) TYK2FABP3FABP4ALDH1A1HPGD
SCHEMBL27507074 0.83 TYK2 (0.43) TYK2FABP3FABP4ALDH1A1HPGD
SCHEMBL5997125 0.82 PPARA (0.47) FABP4HPGDPLK1
SCHEMBL5995750 0.82 ALDH1A1 (0.38) ALDH1A1HPGDLMNAPOLB
SCHEMBL5997804 0.82 DRD3 (0.43) TYK2FABP3FABP4HPGDTRPM4
SCHEMBL5997733 0.81 TSHR (0.38) ALDH1A1HPGDDRD3HTT
SCHEMBL5994307 0.78 SOAT1 (0.40) FABP3FABP4ALDH1A1HPGD
SCHEMBL5994553 0.78 PLA2G2A (0.34) ALDH1A1HPGDHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7109250-B2 Multimer forms of acylphosphines and their derivatives CIBA SPECIALTY CHEMICALS CORP. (US) 2006-09-19 US disclosed
US-7026017-B2 Photoinitiators for acrylic esters; reacting an acyl halide with a metal benzoyl phosphine; cable coatings, screen printing stencils, resist materials, colour filters, electrical encapsulation CIBA SPECIALTY CHEMICALS CORPORATION (US) 2006-04-11 US disclosed
US-6969733-B2 Photoinitiators CIBA SPECIALTY CHEMICALS CORPORATION (US) 2005-11-29 US disclosed
US-20050004247-A1 Multimer forms of acylphosphines and their derivatives CIBA SPECIALTY CHEMICALS CORP. 2005-01-06 US disclosed
EP-1446410-A1 MULTIMER FORMS OF ACYLPHOSPHINES AND THEIR DERIVATIVES Ciba SC Holding AG (CH) 2004-08-18 EP disclosed
US-6737549-B2 PHOTOINITIATORS FOR ACRYLATE COATINGS CIBA SPECIALTY CHEMICALS CORPORATION 2004-05-18 US disclosed
US-20030139485-A1 Photoinitiators WOLF JEAN-PIERRE (CH) 2003-07-24 US disclosed
US-20030130370-A1 Photoinitiators for acrylic esters; reacting an acyl halide with a metal benzoyl phosphine; cable coatings, screen printing stencils, resist materials, colour filters, electrical encapsulation WOLF JEAN-PIERRE (CH) 2003-07-10 US disclosed
WO-2003044030-A1 MULTIMER FORMS OF ACYLPHOSPHINES AND THEIR DERIVATIVES CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2003-05-30 WO disclosed
US-20020026049-A1 Photoinitiators for acrylate coatings CIBA SPECIALTY CHEMICALS CORP. 2002-02-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030139485-A1 Photoinitiators DHCR24, NR1I3, CBR1 TYK2 2818/4885FABP3 3788/4885FABP4 3705/4885
US-20030130370-A1 Photoinitiators for acrylic esters; reacting an acyl halide with a metal benzoyl phosphine; cable coatings, screen printing stencils, resist materials, colour filters, electrical encapsulation SMARCC1, ARPC5L, DHCR24 TYK2 3482/4885FABP3 4397/4885FABP4 3862/4885
US-20020026049-A1 Photoinitiators for acrylate coatings DHCR24, NR5A1, NR2C2 TYK2 2581/4885FABP3 4336/4885FABP4 3747/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.