SCHEMBL5996941

SCHEMBL5996941

CC(C)(C)OC(=O)C(N)CSC(c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.65

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 19/20 0.65
DNMT1 P26358 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4459711 1.00 KIF11 (0.65) KIF11DNMT1
SCHEMBL29635035 1.00 KIF11 (0.65) KIF11DNMT1
Hydrochloric Acid SCHEMBL25242234 0.99 KIF11 (0.64) KIF11DNMT1
Hydrochloric Acid SCHEMBL4459708 0.99 KIF11 (0.64) KIF11DNMT1
Hydrochloric Acid SCHEMBL4459715 0.99 KIF11 (0.64) KIF11DNMT1
SCHEMBL30745107 0.90 KIF11 (0.64) KIF11DNMT1
SCHEMBL8036028 0.89 KIF11 (0.60) KIF11DNMT1
SCHEMBL12872399 0.85 KIF11 (0.85) KIF11DNMT1
SCHEMBL3439368 0.85 KIF11 (0.85) KIF11DNMT1
SCHEMBL9137501 0.85 KIF11 (0.85) KIF11DNMT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023097207-A1 SYNTHETIC PROCESS FOR PRODUCTION OF MODIFIED GCC RECEPTOR AGONISTS IRONWOOD PHARMACEUTICALS, INC. (US) 2023-06-01 WO disclosed
US-20060281926-A1 Synthesis of 2-alkylcysteine via phase transfer catalysis GIMI RAYOMAND H 2006-12-14 US disclosed
US-7115769-B2 Synthesis of 2-alkylcysteine via phase transfer catalysis GENZYME CORPORATION (US) 2006-10-03 US disclosed
EP-1529037-A2 SYNTHESIS OF 2-ALKYLCYSTEINES, 2-(HYDROXYLATED PHENYL)-4-ALKYLTHIAZOLINE-4-CARBOXYLIC ACIDS AND DERIVATIVES THEREOF Genzyme Corporation (US) 2005-05-11 EP disclosed
US-20030236404-A1 Synthesis of 2-alkylcysteine via phase transfer catalysis GENZYME CORPORATION 2003-12-25 US disclosed
WO-2003097622-A2 SYNTHESIS OF 2-ALKYLCYSTEINES, 2-(HYDROXYLATED PHENYL)-4-ALKYLTHIAZOLINE-4-CARBOXYLIC ACIDS AND DERIVATIVES THEREOF GENZYME CORPORATION (US) 2003-11-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030236404-A1 Synthesis of 2-alkylcysteine via phase transfer catalysis DIMT1, ICMT, CNDP2 KIF11 4699/4885DNMT1 1291/4885
US-20060281926-A1 Synthesis of 2-alkylcysteine via phase transfer catalysis DIMT1, ICMT, CNDP2 KIF11 4699/4885DNMT1 1291/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.