Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 3/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.47 |
| ▸ | PPARG | P37231 | 3/20 | 0.47 |
| ▸ | PPARD | Q03181 | 3/20 | 0.47 |
| ▸ | PPARA | Q07869 | 3/20 | 0.47 |
| ▸ | TOP1 | P11387 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | BLM | P54132 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | FABP4 | P15090 | 2/20 | 0.47 |
| ▸ | DUSP3 | P51452 | 2/20 | 0.47 |
| ▸ | PTPN7 | P35236 | 2/20 | 0.47 |
| ▸ | GMNN | O75496 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | APEX1 | P27695 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11609797 | 0.91 | TDP1 (0.40) | PTPN1PPARGPPARDPPARABLM | |
| SCHEMBL5997470 | 0.91 | TDP1 (0.40) | PTPN1PPARGPPARDPPARABLM | |
| SCHEMBL9437219 | 0.91 | TDP1 (0.40) | PTPN1PPARGPPARDPPARABLM | |
| SCHEMBL2455190 | 0.86 | FABP3 (0.56) | PPARGPPARDPPARAMAPTBLM | |
| SCHEMBL3349912 | 0.83 | FABP3 (0.46) | MAPTBLMHSD17B10DUSP3GMNN | |
| SCHEMBL5498777 | 0.83 | ACLY (0.55) | TERTPTPN1PPARGPPARDPPARA | |
| SCHEMBL5504633 | 0.80 | PPARG (0.55) | TERTPTPN1PPARGPPARDPPARA | |
| SCHEMBL20853667 | 0.80 | CES2 (0.41) | — | |
| SCHEMBL9227142 | 0.78 | FFAR1 (0.32) | CYP2C19CHRM1TBXA2RTDP1 | |
| SCHEMBL10711653 | 0.77 | CES2 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7067500-B2 | Betaines as adjuvants to susceptibility testing and antimicrobial therapy | INTEGRATED RESEARCH TECHNOLOGY, LLC (US) | 2006-06-27 | — | — | US | disclosed |
| EP-0756633-B1 | METHOD AND KITS FOR PROCESSING MYCOBACTERIA AND MYCOLIC ACID CONTAINING BACTERIA | INTEGRATED RES TECHNOLOGY LLC (US) | 2005-06-08 | — | — | EP | disclosed |
| US-20030104513-A1 | Betaines as adjuvants to susceptibility testing and antimicrobial therapy | INTEGRATED RESEARCH TECHNOLOGY, LLC | 2003-06-05 | — | — | US | disclosed |
| US-6406880-B1 | MYCOLIC ACID STRUCTURE IN OUTER MEMBRANE, ANTIBIOTIC AND BETAINE | INTEGRATED RESEARCH TECHNOLOGY, LLC | 2002-06-18 | — | — | US | disclosed |
| US-6004771-A | EXTRACTED MYCOBACTERIAL SAMPLE IS SUITABLE FOR DETECTION BY CULTURE AND AMPLIFICATION | INTEGRATED RESEARCH TECHNOLOGY, LLC (US) | 1999-12-21 | — | — | US | disclosed |
| US-5658749-A | DECREASING THE BUOYANCY OF MICROORGANISMS CONTAINING MYCOLIC ACID-LIKE STRUCTURES IN THE OUTER MEMBRANE USING A SOLUTION OF AN SB-18-LIKE OR ROD-LIKE DETERGENT; AMPHOTERIC SURFACTANTS; MEDICAL DIAGNOSIS; CULTURES; AMPLIFICATION | CORNING CLINICAL LABORATORIES, INC. (US) | 1997-08-19 | — | — | US | disclosed |