Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.33 |
| ▸ | HSPA5 | P11021 | 2/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | LCK | P06239 | 1/20 | 0.32 |
| ▸ | FYN | P06241 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5995454 | 0.84 | DPP4 (0.36) | HSD17B10TSHRCYP3A4MAPK1LMNA | |
| SCHEMBL5994132 | 0.83 | CES2 (0.33) | — | |
| SCHEMBL5996215 | 0.82 | TSHR (0.35) | HPGDHSD17B10TSHRCASP1HSPA5 | |
| SCHEMBL5996994 | 0.82 | KMT2A (0.39) | HSD17B10TSHRCYP3A4HIF1AMAPK1 | |
| SCHEMBL27614670 | 0.80 | TSHR (0.34) | HPGDTSHRMEN1ESR1POLB | |
| SCHEMBL5995695 | 0.79 | TSHR (0.33) | HPGDHSD17B10TSHRCASP1CYP3A4 | |
| SCHEMBL5995316 | 0.78 | ALDH1A1 (0.44) | HPGDHSD17B10TSHRCYP1A2DRD1 | |
| SCHEMBL5997553 | 0.78 | ALDH1A1 (0.41) | HSD17B10TSHRCYP3A4HIF1AMAPK1 | |
| SCHEMBL5996807 | 0.78 | ALDH1A1 (0.50) | HPGDTSHRCYP3A4MEN1NPC1 | |
| SCHEMBL27595767 | 0.77 | ALDH1A1 (0.41) | HSD17B10TSHRCYP3A4HIF1AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7109250-B2 | Multimer forms of acylphosphines and their derivatives | CIBA SPECIALTY CHEMICALS CORP. (US) | 2006-09-19 | — | — | US | disclosed |
| US-7026017-B2 | Photoinitiators for acrylic esters; reacting an acyl halide with a metal benzoyl phosphine; cable coatings, screen printing stencils, resist materials, colour filters, electrical encapsulation | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2006-04-11 | — | — | US | disclosed |
| US-6969733-B2 | Photoinitiators | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2005-11-29 | — | — | US | disclosed |
| US-20050004247-A1 | Multimer forms of acylphosphines and their derivatives | CIBA SPECIALTY CHEMICALS CORP. | 2005-01-06 | — | — | US | disclosed |
| EP-1446410-A1 | MULTIMER FORMS OF ACYLPHOSPHINES AND THEIR DERIVATIVES | Ciba SC Holding AG (CH) | 2004-08-18 | — | — | EP | disclosed |
| US-20030139485-A1 | Photoinitiators | WOLF JEAN-PIERRE (CH) | 2003-07-24 | — | — | US | disclosed |
| US-20030130370-A1 | Photoinitiators for acrylic esters; reacting an acyl halide with a metal benzoyl phosphine; cable coatings, screen printing stencils, resist materials, colour filters, electrical encapsulation | WOLF JEAN-PIERRE (CH) | 2003-07-10 | — | — | US | disclosed |
| WO-2003044030-A1 | MULTIMER FORMS OF ACYLPHOSPHINES AND THEIR DERIVATIVES | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2003-05-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030139485-A1 | Photoinitiators | DHCR24, NR1I3, CBR1 | HPGD 2368/4885HSD17B10 611/4885TSHR 1096/4885 |
| US-20030130370-A1 | Photoinitiators for acrylic esters; reacting an acyl halide with a metal benzoyl phosphine; cable coatings, screen printing stencils, resist materials, colour filters, electrical encapsulation | SMARCC1, ARPC5L, DHCR24 | HPGD 3137/4885HSD17B10 435/4885TSHR 4029/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.