SCHEMBL5997245

SCHEMBL5997245

CCP(=O)(C(=O)c1c(Cl)cccc1Cl)C(=O)c1c(OC)cc(OC)cc1OC

nearest known ligand 0.44

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ABCG2 Q9UNQ0 4/20 0.44
ELANE P08246 3/20 0.43
LMNA P02545 1/20 0.42
CYP3A4 P08684 2/20 0.40
MAPT P10636 1/20 0.40
USP2 O75604 1/20 0.40
MAPK1 P28482 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
TAS1R3 Q7RTX0 1/20 0.40
TAS1R1 Q7RTX1 1/20 0.40
TAS1R2 Q8TE23 1/20 0.40
MEN1 O00255 1/20 0.39
PTGS2 P35354 1/20 0.39
KMT2A Q03164 1/20 0.39
CXCL12 P48061 1/20 0.39
CYP2D6 P10635 1/20 0.39
CYP2C19 P33261 1/20 0.39
TOP1 P11387 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5996152 0.90 CA12 (0.45) MAPTSMN1; SMN2CXCL12
SCHEMBL5997535 0.89 ABCG2 (0.41) ABCG2ELANELMNACYP3A4MAPT
SCHEMBL5994328 0.89 MAPT (0.50) ABCG2CYP3A4MAPTUSP2MAPK1
SCHEMBL5994350 0.87 ABCG2 (0.41) ABCG2ELANELMNACYP3A4MAPT
SCHEMBL5996902 0.85 KMT2A (0.43) ABCG2CYP3A4MAPTUSP2MAPK1
SCHEMBL5996374 0.85 TAS1R3 (0.44) ABCG2CYP3A4MAPTUSP2MAPK1
SCHEMBL29933904 0.84 ALDH1A1 (0.47) CYP3A4MAPTSMN1; SMN2TAS1R3TAS1R1
SCHEMBL5997023 0.84 SMN1; SMN2 (0.47) ABCG2LMNACYP3A4MAPTUSP2
SCHEMBL5995788 0.84 CA12 (0.41) LMNAMAPTMAPK1SMN1; SMN2TAS1R3
SCHEMBL5994376 0.84 ABCG2 (0.41) ABCG2ELANELMNACYP3A4MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7026017-B2 Photoinitiators for acrylic esters; reacting an acyl halide with a metal benzoyl phosphine; cable coatings, screen printing stencils, resist materials, colour filters, electrical encapsulation CIBA SPECIALTY CHEMICALS CORPORATION (US) 2006-04-11 US disclosed
US-6969733-B2 Photoinitiators CIBA SPECIALTY CHEMICALS CORPORATION (US) 2005-11-29 US disclosed
US-6737549-B2 PHOTOINITIATORS FOR ACRYLATE COATINGS CIBA SPECIALTY CHEMICALS CORPORATION 2004-05-18 US disclosed
US-20030139485-A1 Photoinitiators WOLF JEAN-PIERRE (CH) 2003-07-24 US disclosed
US-20030130370-A1 Photoinitiators for acrylic esters; reacting an acyl halide with a metal benzoyl phosphine; cable coatings, screen printing stencils, resist materials, colour filters, electrical encapsulation WOLF JEAN-PIERRE (CH) 2003-07-10 US disclosed
US-20020026049-A1 Photoinitiators for acrylate coatings CIBA SPECIALTY CHEMICALS CORP. 2002-02-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030139485-A1 Photoinitiators DHCR24, NR1I3, CBR1 ABCG2 3623/4885ELANE 4528/4885LMNA 763/4885
US-20030130370-A1 Photoinitiators for acrylic esters; reacting an acyl halide with a metal benzoyl phosphine; cable coatings, screen printing stencils, resist materials, colour filters, electrical encapsulation SMARCC1, ARPC5L, DHCR24 ABCG2 3245/4885ELANE 4803/4885LMNA 975/4885
US-20020026049-A1 Photoinitiators for acrylate coatings DHCR24, NR5A1, NR2C2 ABCG2 3003/4885ELANE 3859/4885LMNA 848/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.