Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 10/20 | 0.38 |
| ▸ | MMP9 | P14780 | 9/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | TNF | P01375 | 1/20 | 0.38 |
| ▸ | MMP3 | P08254 | 8/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MMP8 | P22894 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5995988 | 0.86 | TNF (0.35) | TNFKMT2AMEN1AVPR1AALDH1A1 | |
| SCHEMBL5998273 | 0.85 | ALDH1A1 (0.37) | MMP1MMP3KMT2AMEN1ALDH1A1 | |
| SCHEMBL5997126 | 0.85 | NPC1 (0.41) | KMT2AMEN1ALDH1A1NPC1POLB | |
| SCHEMBL5998825 | 0.85 | MEN1 (0.39) | MMP1MMP9MMP3KMT2AMEN1 | |
| SCHEMBL5997892 | 0.85 | ALDH1A1 (0.38) | MMP1MMP3KMT2AMEN1AVPR1A | |
| SCHEMBL5997972 | 0.84 | ALDH1A1 (0.36) | KMT2AMEN1ALDH1A1NPC1POLB | |
| SCHEMBL5997123 | 0.84 | ALDH1A1 (0.48) | MMP1MMP3KMT2AMEN1ALDH1A1 | |
| SCHEMBL5998394 | 0.83 | ACHE (0.40) | KMT2AMEN1AVPR1AALDH1A1MMP2 | |
| SCHEMBL5997711 | 0.83 | TNF (0.41) | MMP1TNFMMP3KMT2AMEN1 | |
| SCHEMBL5998133 | 0.82 | KMT2A (0.37) | KMT2AMEN1AVPR1AALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7094908-B2 | Reduction of carbonyl compounds using the carbonyl reductase of Kluyveromyces marxianus | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2006-08-22 | — | — | US | disclosed |
| US-20030139464-A1 | Reduction of carbonyl compounds using the carbonyl reductase of kluyveromyces marxianus | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY | 2003-07-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030139464-A1 | Reduction of carbonyl compounds using the carbonyl reductase of kluyveromyces marxianus | CBR1, CBR3, DCXR | MMP1 1625/4885MMP9 2230/4885DRD2 3742/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.