SCHEMBL5997373

SCHEMBL5997373

CCOc1cccc(OCC)c1C(=O)P(=O)(CC)C(=O)c1c(C)cccc1C

nearest known ligand 0.41

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
GLA P06280 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
HCRTR1 O43613 2/20 0.40
GRK6 P43250 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.38
TAS1R3 Q7RTX0 1/20 0.38
TAS1R1 Q7RTX1 1/20 0.38
TAS1R2 Q8TE23 1/20 0.38
GAA P10253 1/20 0.37
CA9 Q16790 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
KCNK3 O14649 1/20 0.36
KCNK9 Q9NPC2 1/20 0.36
PTK2 Q05397 1/20 0.36
TRPM4 Q8TD43 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5995735 0.90 HPGD (0.40) GLAL3MBTL1HCRTR1GRK6SMN1; SMN2
SCHEMBL5996289 0.87 RXFP1 (0.42) GLAL3MBTL1HCRTR1GRK6SMN1; SMN2
SCHEMBL5995529 0.87 TAS1R3 (0.50) SMN1; SMN2TAS1R3TAS1R1TAS1R2CA9
SCHEMBL5994800 0.87 SMN1; SMN2 (0.51) GLAL3MBTL1HCRTR1SMN1; SMN2CA9
SCHEMBL5994900 0.86 TAS1R3 (0.39) GLAL3MBTL1HCRTR1SMN1; SMN2TAS1R3
SCHEMBL5997536 0.86 TSHR (0.39) GLAL3MBTL1HCRTR1SMN1; SMN2TAS1R3
SCHEMBL152303 0.86 F2R (0.41) L3MBTL1TAS1R3TAS1R1TAS1R2GAA
SCHEMBL5997023 0.82 SMN1; SMN2 (0.47) SMN1; SMN2KCNK3KCNK9
SCHEMBL7189008 0.82 L3MBTL1 (0.44) GLAL3MBTL1HCRTR1SMN1; SMN2TRPM4
SCHEMBL5995649 0.81 L3MBTL1 (0.39) GLAL3MBTL1HCRTR1SMN1; SMN2TAS1R3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7026017-B2 Photoinitiators for acrylic esters; reacting an acyl halide with a metal benzoyl phosphine; cable coatings, screen printing stencils, resist materials, colour filters, electrical encapsulation CIBA SPECIALTY CHEMICALS CORPORATION (US) 2006-04-11 US disclosed
US-6969733-B2 Photoinitiators CIBA SPECIALTY CHEMICALS CORPORATION (US) 2005-11-29 US disclosed
US-6737549-B2 PHOTOINITIATORS FOR ACRYLATE COATINGS CIBA SPECIALTY CHEMICALS CORPORATION 2004-05-18 US disclosed
US-20030139485-A1 Photoinitiators WOLF JEAN-PIERRE (CH) 2003-07-24 US disclosed
US-20030130370-A1 Photoinitiators for acrylic esters; reacting an acyl halide with a metal benzoyl phosphine; cable coatings, screen printing stencils, resist materials, colour filters, electrical encapsulation WOLF JEAN-PIERRE (CH) 2003-07-10 US disclosed
US-20020026049-A1 Photoinitiators for acrylate coatings CIBA SPECIALTY CHEMICALS CORP. 2002-02-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030139485-A1 Photoinitiators DHCR24, NR1I3, CBR1 GLA 3686/4885L3MBTL1 1852/4885HCRTR1 152/4885
US-20030130370-A1 Photoinitiators for acrylic esters; reacting an acyl halide with a metal benzoyl phosphine; cable coatings, screen printing stencils, resist materials, colour filters, electrical encapsulation SMARCC1, ARPC5L, DHCR24 GLA 3872/4885L3MBTL1 1879/4885HCRTR1 1591/4885
US-20020026049-A1 Photoinitiators for acrylate coatings DHCR24, NR5A1, NR2C2 GLA 3227/4885L3MBTL1 2570/4885HCRTR1 362/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.