SCHEMBL5997378

SCHEMBL5997378

Cc1cc2cn([C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O)c(=O)nc2[nH]1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.51
MTOR P42345 2/20 0.51
ALDH1A1 P00352 2/20 0.51
THRB P10828 1/20 0.51
MDM2 Q00987 1/20 0.51
NCOA1 Q15788 1/20 0.51
NCOA3 Q9Y6Q9 1/20 0.51
GMNN O75496 1/20 0.51
TP53 P04637 1/20 0.51
NFKB1 P19838 1/20 0.51
DNMT1 P26358 1/20 0.51
THPO P40225 1/20 0.51
HTT P42858 1/20 0.51
RAB9A P51151 1/20 0.51
BLM P54132 1/20 0.51
HBB P68871 1/20 0.51
PMP22 Q01453 1/20 0.51
MAPT P10636 1/20 0.48
CDA P32320 1/20 0.48
PYGM P11217 3/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16631345 1.00 LMNA (0.51) LMNAMTORALDH1A1THRBMDM2
SCHEMBL16556356 0.90 CDA (0.42) LMNAMTORALDH1A1THRBMDM2
SCHEMBL16631481 0.89 LMNA (0.49) LMNAMTORALDH1A1THRBMDM2
SCHEMBL27054170 0.88 TK2 (0.40) LMNAMTORALDH1A1THRBMDM2
SCHEMBL27058716 0.88 TK2 (0.40) LMNAMTORALDH1A1THRBMDM2
SCHEMBL16631358 0.88 LMNA (0.48) LMNAMTORALDH1A1THRBMDM2
SCHEMBL16631418 0.86 CDK1 (0.48) LMNAMTORALDH1A1THRBMDM2
SCHEMBL16631305 0.86 LMNA (0.51) LMNAMTORALDH1A1THRBMDM2
SCHEMBL21035550 0.86 P2RY6 (0.39) LMNAMTORALDH1A1THRBMDM2
SCHEMBL18852429 0.86 LMNA (0.37) LMNAMTORALDH1A1THRBMDM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 445 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4705481-A2 CIRCULAR RNA COMPOSITIONS AND METHODS Orna Therapeutics, Inc. (US) 2026-03-11 EP claimed
WO-2025235365-A1 METHODS AND SYSTEMS FOR IMPROVED METHYLATION SEQUENCING FREENOME HOLDINGS, INC. (US) 2025-11-13 WO claimed
EP-4623076-A1 DOUBLE-STRANDED DNA DEAMINASES AND USES THEREOF New England Biolabs, Inc. (US) 2025-10-01 EP claimed
WO-2025151711-A1 NUCLEIC ACID VACCINES TARGETING METHANOGENS Arkea Bio Corp. (US) 2025-07-17 WO claimed
WO-2025122721-A1 CHIMERIC PROTEINS AND USES THEREOF SHATTUCK LABS, INC. (US) 2025-06-12 WO claimed
EP-4554616-A1 COMPOSITIONS AND METHODS FOR REDUCING METHANE EMISSIONS IN RUMINANT POPULATIONS Arkea Bio Corp. (US) 2025-05-21 EP claimed
EP-4540415-A1 METHODS AND COMPOSITIONS FOR THE SIMULTANEOUS IDENTIFICATION AND MAPPING OF DNA METHYLATION New England Biolabs, Inc. (US) 2025-04-23 EP claimed
WO-2025049610-A1 MULTI-ACTION PEPTIDES SHATTUCK LABS, INC. (US) 2025-03-06 WO claimed
CN-113727972-B Novel hydrazone derivatives having terminal amine groups substituted with aryl or heteroaryl groups and use thereof 韩国科学技术研究院 2024-12-27 CN claimed
WO-2024233308-A2 CIRCULAR RNA COMPOSITIONS AND METHODS ORNA THERAPEUTICS, INC. (US) 2024-11-14 WO claimed
WO-2024015366-A1 COMPOSITIONS AND METHODS FOR REDUCING METHANE EMISSIONS IN RUMINANT POPULATIONS Arkea Bio Corp. (US) 2024-01-18 WO claimed
WO-2023245056-A1 METHODS AND COMPOSITIONS FOR THE SIMULTANEOUS IDENTIFICATION AND MAPPING OF DNA METHYLATION NEW ENGLAND BIOLABS, INC. (US) 2023-12-21 WO claimed
WO-2023215498-A2 COMPOSITIONS AND METHODS FOR CD28 ANTAGONISM MODERNATX, INC. (US) 2023-11-09 WO claimed
US-20230357838-A1 Double-Stranded DNA Deaminases and Uses Thereof NEW ENGLAND BIOLABS, INC. (US) 2023-11-09 US claimed
WO-2023178182-A1 COMPOSITIONS AND METHODS FOR DETECTION AND TREATMENT OF CORONAVIRUS INFECTION 10X GENOMICS, INC. (US) 2023-09-21 WO claimed
US-20230257730-A1 Double-Stranded DNA Deaminases NEW ENGLAND BIOLABS, INC. (US) 2023-08-17 US claimed
WO-2023097226-A2 DOUBLE-STRANDED DNA DEAMINASES NEW ENGLAND BIOLABS, INC. (US) 2023-06-01 WO claimed
WO-2023077156-A1 MODIFIED MRNA THERAPEUTICS SHATTUCK LABS, INC. (US) 2023-05-04 WO claimed
WO-2023023055-A1 COMPOSITIONS AND METHODS FOR OPTIMIZING TROPISM OF DELIVERY SYSTEMS FOR RNA RENAGADE THERAPEUTICS MANAGEMENT INC. (US) 2023-02-23 WO claimed
CN-109863161-B Labeled polynucleotides useful for nucleic acid sequencing 豪夫迈·罗氏有限公司 2022-06-03 CN claimed