Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY6 | Q15077 | 5/20 | 0.39 |
| ▸ | P2RY2 | P41231 | 5/20 | 0.39 |
| ▸ | P2RY4 | P51582 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MTOR | P42345 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.37 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.37 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.37 |
| ▸ | GMNN | O75496 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.37 |
| ▸ | THPO | P40225 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | HBB | P68871 | 1/20 | 0.37 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5997378 | 0.86 | LMNA (0.51) | LMNAMTORTHRBMDM2NCOA1 | |
| SCHEMBL16631345 | 0.86 | LMNA (0.51) | LMNAMTORTHRBMDM2NCOA1 | |
| SCHEMBL10132924 | 0.86 | DNPH1 (0.53) | P2RY6P2RY2P2RY4TAS1R3TAS1R1 | |
| SCHEMBL18158961 | 0.86 | DNPH1 (0.53) | P2RY6P2RY2P2RY4TAS1R3TAS1R1 | |
| SCHEMBL18852429 | 0.81 | LMNA (0.37) | LMNAMTORTHRBMDM2NCOA1 | |
| SCHEMBL18080319 | 0.81 | P2RY2 (0.61) | P2RY6P2RY2P2RY4 | |
| SCHEMBL21276421 | 0.80 | LMNA (0.39) | LMNAMTORTHRBMDM2NCOA1 | |
| SCHEMBL15305428 | 0.80 | P2RY2 (0.41) | P2RY6P2RY2P2RY4LMNAMTOR | |
| SCHEMBL24798428 | 0.78 | LMNA (0.45) | P2RY6P2RY2LMNAMTORTHRB | |
| SCHEMBL27054170 | 0.77 | TK2 (0.40) | LMNAMTORTHRBMDM2NCOA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4108671-A1 | MODIFIED NUCLEOSIDES, NUCLEOTIDES, AND NUCLEIC ACIDS, AND USES THEREOF | ModernaTX, Inc. (US) | 2022-12-28 | — | — | EP | disclosed |
| EP-3590949-B1 | RIBONUCLEIC ACIDS CONTAINING N1-METHYL-PSEUDOURACILS AND USES THEREOF | MODERNATX INC (US) | 2022-05-18 | — | — | EP | disclosed |
| EP-3590949-A1 | RIBONUCLEIC ACIDS CONTAINING N1-METHYL-PSEUDOURACILS AND USES THEREOF | ModernaTX, Inc. (US) | 2020-01-08 | — | — | EP | disclosed |
| EP-2622064-B1 | MODIFIED NUCLEOSIDES, NUCLEOTIDES, AND NUCLEIC ACIDS, AND USES THEREOF | MODERNATX INC (US) | 2019-05-29 | — | — | EP | disclosed |