SCHEMBL5997380

SCHEMBL5997380

CCOc1cccc(OCC)c1C(=O)CC[PH](=O)C(=O)c1c(C)cccc1C

nearest known ligand 0.40

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.40
L3MBTL1 Q9Y468 2/20 0.37
GLA P06280 2/20 0.37
CYP2C19 P33261 1/20 0.36
NPC1 O15118 1/20 0.36
RAB9A P51151 1/20 0.36
POLB P06746 1/20 0.36
PTPN1 P18031 1/20 0.35
EGFR P00533 1/20 0.34
HCRTR1 O43613 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
DAO P14920 1/20 0.34
KDM4E B2RXH2 1/20 0.34
KMT2A Q03164 1/20 0.34
USP2 O75604 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5995748 0.91 MAPT (0.37) GAAL3MBTL1GLACYP2C19POLB
SCHEMBL5996293 0.88 RXFP1 (0.37) GAAL3MBTL1GLACYP2C19POLB
SCHEMBL5994818 0.87 SMN1; SMN2 (0.43) GAAL3MBTL1GLACYP2C19
SCHEMBL5997029 0.82 LMNA (0.41) CYP2C19KDM4EKMT2A
SCHEMBL5995533 0.81 CA12 (0.42) GAAKDM4E
SCHEMBL5995888 0.81 GABRA1 (0.34) L3MBTL1POLBTDP1KMT2A
SCHEMBL5996721 0.81 CTNNB1 (0.39)
SCHEMBL5997931 0.80 CYP2D6 (0.43) L3MBTL1CYP2C19NPC1RAB9AKMT2A
SCHEMBL5997924 0.78 MAPT (0.36) GAAL3MBTL1RAB9APOLBKDM4E
SCHEMBL5997542 0.78 MAPT (0.36) GAAL3MBTL1RAB9APOLBKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7026017-B2 Photoinitiators for acrylic esters; reacting an acyl halide with a metal benzoyl phosphine; cable coatings, screen printing stencils, resist materials, colour filters, electrical encapsulation CIBA SPECIALTY CHEMICALS CORPORATION (US) 2006-04-11 US disclosed
US-6969733-B2 Photoinitiators CIBA SPECIALTY CHEMICALS CORPORATION (US) 2005-11-29 US disclosed
US-6737549-B2 PHOTOINITIATORS FOR ACRYLATE COATINGS CIBA SPECIALTY CHEMICALS CORPORATION 2004-05-18 US disclosed
US-20030139485-A1 Photoinitiators WOLF JEAN-PIERRE (CH) 2003-07-24 US disclosed
US-20030130370-A1 Photoinitiators for acrylic esters; reacting an acyl halide with a metal benzoyl phosphine; cable coatings, screen printing stencils, resist materials, colour filters, electrical encapsulation WOLF JEAN-PIERRE (CH) 2003-07-10 US disclosed
US-20020026049-A1 Photoinitiators for acrylate coatings CIBA SPECIALTY CHEMICALS CORP. 2002-02-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030139485-A1 Photoinitiators DHCR24, NR1I3, CBR1 GAA 4801/4885L3MBTL1 1852/4885GLA 3686/4885
US-20030130370-A1 Photoinitiators for acrylic esters; reacting an acyl halide with a metal benzoyl phosphine; cable coatings, screen printing stencils, resist materials, colour filters, electrical encapsulation SMARCC1, ARPC5L, DHCR24 GAA 4108/4885L3MBTL1 1879/4885GLA 3872/4885
US-20020026049-A1 Photoinitiators for acrylate coatings DHCR24, NR5A1, NR2C2 GAA 4741/4885L3MBTL1 2570/4885GLA 3227/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.