Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 5/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.38 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9483100 | 0.95 | CETP (0.49) | CETPITGB1ITGA4 | |
| SCHEMBL6432439 | 0.89 | LMNA (0.41) | TSHRSMN1; SMN2NPC1RAB9AKDM4E | |
| SCHEMBL5995821 | 0.84 | HPGD (0.41) | TSHRITGB1ITGA4SMN1; SMN2KDM4E | |
| SCHEMBL9483049 | 0.81 | CETP (0.42) | CETPTSHRHPGD | |
| SCHEMBL5996505 | 0.81 | ERAP2 (0.38) | SMN1; SMN2NPC1RAB9APOLBMEN1 | |
| SCHEMBL5993499 | 0.81 | HPGD (0.40) | CETPITGB1ITGA4SMN1; SMN2KDM4E | |
| SCHEMBL5996449 | 0.81 | HPGD (0.40) | TSHRITGB1ITGA4SMN1; SMN2KDM4E | |
| SCHEMBL5994231 | 0.81 | HPGD (0.40) | TSHRITGB1ITGA4SMN1; SMN2KDM4E | |
| SCHEMBL7182680 | 0.81 | TSHR (0.41) | CETPTSHRITGB1ITGA4SMN1; SMN2 | |
| SCHEMBL5996700 | 0.80 | LPAR3 (0.40) | CETPITGB1ITGA4SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7026017-B2 | Photoinitiators for acrylic esters; reacting an acyl halide with a metal benzoyl phosphine; cable coatings, screen printing stencils, resist materials, colour filters, electrical encapsulation | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2006-04-11 | — | — | US | disclosed |
| US-6969733-B2 | Photoinitiators | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2005-11-29 | — | — | US | disclosed |
| CN-1198831-C | Organic metal monoacylalkylphosphine compound | CIBA SC HOLDING AG (CH) | 2005-04-27 | — | — | CN | disclosed |
| US-6737549-B2 | PHOTOINITIATORS FOR ACRYLATE COATINGS | CIBA SPECIALTY CHEMICALS CORPORATION | 2004-05-18 | — | — | US | disclosed |
| US-20030139485-A1 | Photoinitiators | WOLF JEAN-PIERRE (CH) | 2003-07-24 | — | — | US | disclosed |
| US-20030130370-A1 | Photoinitiators for acrylic esters; reacting an acyl halide with a metal benzoyl phosphine; cable coatings, screen printing stencils, resist materials, colour filters, electrical encapsulation | WOLF JEAN-PIERRE (CH) | 2003-07-10 | — | — | US | disclosed |
| US-20020026049-A1 | Photoinitiators for acrylate coatings | CIBA SPECIALTY CHEMICALS CORP. | 2002-02-28 | — | — | US | disclosed |
| CN-1329005-A | Organic metal monoacylalkylphosphine compound | CIBA SC HOLDING AG (CH) | 2002-01-02 | — | — | CN | disclosed |
| US-5414133-A | Protected phosphine oxides | CIBA-GEIGY CORPORATION (US) | 1995-05-09 | — | — | US | disclosed |
| US-5298663-A | Process for the preparation of protected phosphine oxides | CIBA-GEIGY CORPORATION (US) | 1994-03-29 | — | — | US | disclosed |
| US-5218009-A | Photoinitiators for the photopolymerization of ethylenically unsaturated compounds | CIBA-GEIGY CORPORATION (US) | 1993-06-08 | — | — | US | disclosed |
| EP-0501702-A2 | Process for the preparation of protected phosphine oxides | CIBA-GEIGY AG (CH) | 1992-09-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030139485-A1 | Photoinitiators | DHCR24, NR1I3, CBR1 | CETP 2536/4885TSHR 1096/4885ITGB1 1746/4885 |
| US-20030130370-A1 | Photoinitiators for acrylic esters; reacting an acyl halide with a metal benzoyl phosphine; cable coatings, screen printing stencils, resist materials, colour filters, electrical encapsulation | SMARCC1, ARPC5L, DHCR24 | CETP 3462/4885TSHR 4029/4885ITGB1 1859/4885 |
| US-20020026049-A1 | Photoinitiators for acrylate coatings | DHCR24, NR5A1, NR2C2 | CETP 2363/4885TSHR 1670/4885ITGB1 340/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.