SCHEMBL5996505

SCHEMBL5996505

Cc1cc(C)c(C(=O)P(=O)(Cc2ccccc2)CC(C)C)c(C)c1

nearest known ligand 0.38

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ERAP2 Q6P179 3/20 0.38
ERAP1 Q9NZ08 3/20 0.38
ANPEP P15144 2/20 0.38
MMP1 P03956 4/20 0.37
MEN1 O00255 3/20 0.37
KMT2A Q03164 3/20 0.37
ATM Q13315 1/20 0.37
POLB P06746 1/20 0.36
LMNA P02545 2/20 0.36
CYP1A2 P05177 1/20 0.35
NPC1 O15118 1/20 0.35
RAB9A P51151 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
CYP2C19 P33261 1/20 0.35
NR3C1 P04150 1/20 0.35
IL1RN P18510 2/20 0.35
HSD17B10 Q99714 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14570828 0.89 MMP1 (0.37) ERAP2ERAP1MMP1MEN1KMT2A
SCHEMBL6432439 0.89 LMNA (0.41) ERAP2ERAP1ANPEPMEN1KMT2A
SCHEMBL5994721 0.85 MMP1 (0.38) ERAP2ERAP1ANPEPMMP1MEN1
SCHEMBL5994494 0.84 KMT2A (0.38) MEN1KMT2ALMNACYP1A2SMN1; SMN2
SCHEMBL5997569 0.81 CETP (0.42) MEN1KMT2APOLBLMNANPC1
SCHEMBL5996237 0.80 MEN1 (0.39) MEN1KMT2ALMNACYP1A2SMN1; SMN2
SCHEMBL7625246 0.80 LMNA (0.41) ERAP2ERAP1ANPEPMEN1KMT2A
SCHEMBL9483100 0.79 CETP (0.49)
SCHEMBL7177532 0.79 ALDH1A1 (0.43) ERAP2ERAP1ANPEPMMP1MEN1
SCHEMBL9483229 0.79 LMNA (0.41) ERAP2ERAP1ANPEPMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7026017-B2 Photoinitiators for acrylic esters; reacting an acyl halide with a metal benzoyl phosphine; cable coatings, screen printing stencils, resist materials, colour filters, electrical encapsulation CIBA SPECIALTY CHEMICALS CORPORATION (US) 2006-04-11 US disclosed
US-6969733-B2 Photoinitiators CIBA SPECIALTY CHEMICALS CORPORATION (US) 2005-11-29 US disclosed
CN-1198831-C Organic metal monoacylalkylphosphine compound CIBA SC HOLDING AG (CH) 2005-04-27 CN disclosed
US-6737549-B2 PHOTOINITIATORS FOR ACRYLATE COATINGS CIBA SPECIALTY CHEMICALS CORPORATION 2004-05-18 US disclosed
US-20030139485-A1 Photoinitiators WOLF JEAN-PIERRE (CH) 2003-07-24 US disclosed
US-20030130370-A1 Photoinitiators for acrylic esters; reacting an acyl halide with a metal benzoyl phosphine; cable coatings, screen printing stencils, resist materials, colour filters, electrical encapsulation WOLF JEAN-PIERRE (CH) 2003-07-10 US disclosed
US-20020026049-A1 Photoinitiators for acrylate coatings CIBA SPECIALTY CHEMICALS CORP. 2002-02-28 US disclosed
CN-1329005-A Organic metal monoacylalkylphosphine compound CIBA SC HOLDING AG (CH) 2002-01-02 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030139485-A1 Photoinitiators DHCR24, NR1I3, CBR1 ERAP2 4760/4885ERAP1 4721/4885ANPEP 4485/4885
US-20030130370-A1 Photoinitiators for acrylic esters; reacting an acyl halide with a metal benzoyl phosphine; cable coatings, screen printing stencils, resist materials, colour filters, electrical encapsulation SMARCC1, ARPC5L, DHCR24 ERAP2 4431/4885ERAP1 4572/4885ANPEP 4557/4885
US-20020026049-A1 Photoinitiators for acrylate coatings DHCR24, NR5A1, NR2C2 ERAP2 4812/4885ERAP1 4764/4885ANPEP 4004/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.