SCHEMBL5998091

SCHEMBL5998091

COC(=O)[C@H]1CN(c2ccc3c(c2)CC(=O)N3C)C(=O)O1

nearest known ligand 0.41

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
F10 P00742 2/20 0.41
SMYD3 Q9H7B4 1/20 0.40
GAA P10253 2/20 0.39
MAOA P21397 3/20 0.39
APOBEC3A P31941 1/20 0.38
APOBEC3G Q9HC16 1/20 0.38
MAOB P27338 2/20 0.37
ALDH1A1 P00352 1/20 0.36
LMNA P02545 3/20 0.36
PTGS1 P23219 1/20 0.36
CALML3 P27482 1/20 0.36
SDHA P31040 1/20 0.36
GRM2 Q14416 1/20 0.35
POLB P06746 1/20 0.35
PKM P14618 2/20 0.35
HTR6 P50406 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3039865 0.90 F10 (0.40) F10MAOAMAOBHTR6
SCHEMBL5998601 0.87 MAOA (0.51) F10SMYD3GAAMAOAAPOBEC3A
SCHEMBL5999489 0.87 F10 (0.41) F10SMYD3GAAMAOAMAOB
SCHEMBL5999288 0.86 GRM2 (0.39) F10GAAMAOAMAOBALDH1A1
SCHEMBL5517629 0.86 GRM2 (0.39) F10GAAMAOAMAOBALDH1A1
SCHEMBL5998454 0.86 MAOA (0.37) MAOAMAOBLMNAPTGS1CALML3
SCHEMBL5509015 0.86 MAOA (0.37) F10MAOAMAOBLMNAPTGS1
SCHEMBL5503079 0.86 MAOA (0.39) F10MAOAMAOBLMNAPTGS1
SCHEMBL5503015 0.86 BRD4 (0.41) GAAMAOAMAOBALDH1A1LMNA
SCHEMBL5509010 0.86 MAOA (0.37) F10MAOAMAOBLMNAPTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060030609-A1 Oxazolidinones containing oxindoles as antibacterial agents LUEHR GARY W 2006-02-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060030609-A1 Oxazolidinones containing oxindoles as antibacterial agents OXA1L, OXSR1, OXER1 F10 1545/4885SMYD3 3313/4885GAA 4408/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.