SCHEMBL5998328

SCHEMBL5998328

CC(C)CCCC(C)CCC1(CCC(C)CCCC(C)C)c2ccccc2-c2ccc(Br)cc21

nearest known ligand 0.39

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 3/20 0.39
PTGS1 P23219 1/20 0.37
PDE4A P27815 1/20 0.37
SNCA P37840 1/20 0.37
PDE3A Q14432 1/20 0.37
APEX1 P27695 1/20 0.33
PTPRC P08575 1/20 0.33
LMNA P02545 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15048485 0.93 LMNA (0.37) PDK2PTGS1PDE4ASNCAPDE3A
SCHEMBL15048628 0.93 LMNA (0.37) PDK2PTGS1PDE4ASNCAPDE3A
SCHEMBL4428913 0.93 LMNA (0.37) PDK2PTGS1PDE4ASNCAPDE3A
SCHEMBL15048488 0.93 LMNA (0.37) PDK2PTGS1PDE4ASNCAPDE3A
SCHEMBL13308779 0.89 PDK2 (0.44) PDK2APEX1PTPRC
SCHEMBL7161784 0.85 PTGS1 (0.31) PTGS1PDE4ASNCAPDE3A
SCHEMBL15048525 0.83 PTGS1 (0.33) PTGS1PDE4ASNCAPDE3A
SCHEMBL15048559 0.83 PTGS1 (0.33) PTGS1PDE4ASNCAPDE3A
SCHEMBL15048496 0.83 PTGS1 (0.33) PTGS1PDE4ASNCAPDE3A
SCHEMBL1115844 0.82 PDK2 (0.36) PDK2PTPRCLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060073357-A1 Carbazole compounds and use of such compounds in organic electroluminiscent devices KONINKLIJKE PHILIPS ELECTRONICS, N.V. (NL) 2006-04-06 US disclosed
EP-1594939-A2 CARBAZOLE COMPOUNDS AND USE OF SUCH COMPOUNDS IN ORGANIC ELECTROLUMINESCENT DEVICES Koninklijke Philips Electronics N.V. (NL) 2005-11-16 EP disclosed
WO-2004072205-A2 CARBAZOLE COMPOUNDS AND USE OF SUCH COMPOUNDS IN ORGANIC ELECTROLUMINESCENT DEVICES KONINKLIJKE PHILIPS ELECTRONICS N.V. (NL) 2004-08-26 WO disclosed