Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | SNCA | P37840 | 1/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15048485 | 1.00 | LMNA (0.37) | LMNAPTGS1PDE4ASNCAPDE3A | |
| SCHEMBL4428913 | 1.00 | LMNA (0.37) | LMNAPTGS1PDE4ASNCAPDE3A | |
| SCHEMBL15048488 | 1.00 | LMNA (0.37) | LMNAPTGS1PDE4ASNCAPDE3A | |
| SCHEMBL5998328 | 0.93 | PDK2 (0.39) | LMNAPTGS1PDE4ASNCAPDE3A | |
| SCHEMBL15048496 | 0.89 | PTGS1 (0.33) | PTGS1PDE4ASNCAPDE3A | |
| SCHEMBL15048525 | 0.89 | PTGS1 (0.33) | PTGS1PDE4ASNCAPDE3A | |
| SCHEMBL15048559 | 0.89 | PTGS1 (0.33) | PTGS1PDE4ASNCAPDE3A | |
| SCHEMBL1115844 | 0.88 | PDK2 (0.36) | LMNAPDK2 | |
| SCHEMBL7161784 | 0.86 | PTGS1 (0.31) | PTGS1PDE4ASNCAPDE3A | |
| SCHEMBL340410 | 0.85 | MMP9 (0.40) | PDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8471035-B1 | Two-photon absorbing arylamine-endcapped and dialkylfluorene-bridged benzobisthiazole compounds with high oleophilicity | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) | 2013-06-25 | — | — | US | disclosed |