Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.46 |
| ▸ | RXRB | P28702 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | IDO1 | P14902 | 2/20 | 0.42 |
| ▸ | APP | P05067 | 4/20 | 0.42 |
| ▸ | PPARG | P37231 | 3/20 | 0.40 |
| ▸ | PPARA | Q07869 | 3/20 | 0.40 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.40 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.40 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2718708 | 1.00 | RXRA (0.46) | RXRARXRBCYP3A4IDO1APP | |
| SCHEMBL2719020 | 1.00 | RXRA (0.46) | RXRARXRBCYP3A4IDO1APP | |
| SCHEMBL27830644 | 0.85 | SLC7A5 (0.47) | IDO1PPARGPPARASLC1A3SLC1A2 | |
| SCHEMBL138280 | 0.83 | KMT2A (0.56) | SLC1A3SLC1A2SLC1A1MEN1CYP1A2 | |
| SCHEMBL27757196 | 0.83 | KMT2A (0.56) | SLC1A3SLC1A2SLC1A1MEN1CYP1A2 | |
| SCHEMBL138281 | 0.83 | KMT2A (0.56) | SLC1A3SLC1A2SLC1A1MEN1CYP1A2 | |
| SCHEMBL1706675 | 0.83 | KMT2A (0.56) | SLC1A3SLC1A2SLC1A1MEN1CYP1A2 | |
| SCHEMBL1533101 | 0.82 | NR4A2 (0.46) | CYP3A4IDO1PPARGPPARACYP2D6 | |
| SCHEMBL1967754 | 0.82 | RXRA (0.46) | RXRARXRBIDO1PPARGPPARA | |
| SCHEMBL21506677 | 0.82 | RXRA (0.54) | RXRARXRBIDO1PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060194857-A1 | Novel heteroaryl derivative | DAINIPPON SUMITOMO PHARMA CO. LTD. (JP) | 2006-08-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060194857-A1 | Novel heteroaryl derivative | NR0B1, UGT1A10, NR0B2 | RXRA 307/4885RXRB 262/4885CYP3A4 21/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.