Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.50 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.50 |
| ▸ | GAPDH | P04406 | 1/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.45 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.45 |
| ▸ | GPR84 | Q9NQS5 | 8/20 | 0.45 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | GMNN | O75496 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | THPO | P40225 | 1/20 | 0.42 |
| ▸ | MTOR | P42345 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2529542 | 1.00 | MAPT (0.50) | MAPTTRPA1DDAH1GAPDHFFAR1 | |
| SCHEMBL148996 | 1.00 | MAPT (0.50) | MAPTTRPA1DDAH1GAPDHFFAR1 | |
| SCHEMBL8459219 | 1.00 | MAPT (0.50) | MAPTTRPA1DDAH1GAPDHFFAR1 | |
| SCHEMBL6050150 | 1.00 | MAPT (0.50) | MAPTTRPA1DDAH1GAPDHFFAR1 | |
| SCHEMBL184105 | 1.00 | MAPT (0.50) | MAPTTRPA1DDAH1GAPDHFFAR1 | |
| SCHEMBL11430050 | 1.00 | MAPT (0.50) | MAPTTRPA1DDAH1GAPDHFFAR1 | |
| SCHEMBL811911 | 1.00 | MAPT (0.50) | MAPTTRPA1DDAH1GAPDHFFAR1 | |
| SCHEMBL6050380 | 1.00 | MAPT (0.50) | MAPTTRPA1DDAH1GAPDHFFAR1 | |
| SCHEMBL20610561 | 1.00 | MAPT (0.50) | MAPTTRPA1DDAH1GAPDHFFAR1 | |
| SCHEMBL9295672 | 1.00 | MAPT (0.50) | MAPTTRPA1DDAH1GAPDHFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140114086-A1 | Clinprost, Isocarbacyclin And Analogs Thereof And Methods Of Making The Same | THE UNIVERSITY OF NORTH CAROLINA AT GREENSBORO | 2014-04-24 | — | — | US | disclosed |
| US-20140114086-A1 | Clinprost, Isocarbacyclin And Analogs Thereof And Methods Of Making The Same | THE UNIVERSITY OF NORTH CAROLINA AT GREENSBORO | 2014-04-24 | — | — | US | disclosed |
| US-7038043-B1 | Glycosylated indolocarbazole synthesis | YALE UNIVERSITY (US) | 2006-05-02 | — | — | US | disclosed |
| US-6037468-A | Glycosylated indolocarbazole synthesis | YALE UNIVERSITY (US) | 2000-03-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140114086-A1 | Clinprost, Isocarbacyclin And Analogs Thereof And Methods Of Making The Same | PTGIS, CRH, PTGIR | MAPT 4349/4885TRPA1 4370/4885DDAH1 2484/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.