Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 7/20 | 0.49 |
| ▸ | KIF11 | P52732 | 1/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4196221 | 0.87 | CYP19A1 (0.55) | CYP19A1KIF11CYP11B1CYP11B2LMNA | |
| SCHEMBL5999494 | 0.85 | CYP19A1 (0.50) | CYP19A1KIF11CYP11B1CYP11B2LMNA | |
| Hydrochloric Acid SCHEMBL20186907 | 0.85 | CYP19A1 (0.53) | CYP19A1KIF11CYP11B1CYP11B2LMNA | |
| SCHEMBL5998626 | 0.84 | CYP19A1 (0.54) | CYP19A1KIF11CYP11B1CYP11B2LMNA | |
| Hydrochloric Acid SCHEMBL27518112 | 0.84 | CYP19A1 (0.49) | CYP19A1KIF11CYP11B1CYP11B2LMNA | |
| SCHEMBL5999982 | 0.83 | CYP19A1 (0.42) | CYP19A1CYP11B1CYP11B2LMNACYP1A2 | |
| SCHEMBL5999469 | 0.80 | CYP19A1 (0.42) | CYP19A1KIF11CYP11B1CYP11B2CYP1A2 | |
| SCHEMBL6000109 | 0.80 | KIF11 (0.42) | CYP19A1KIF11CYP11B1CYP11B2LMNA | |
| SCHEMBL25981366 | 0.79 | KCNN4 (0.44) | KIF11CYP3A4TDP1 | |
| SCHEMBL6716682 | 0.76 | CYP19A1 (0.49) | CYP19A1CYP11B1CYP11B2LMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060058357-A1 | Delta2-1,2,3-triazoline anticonvulsants and their active metabolite analogues, the aminoalkylpyridines, are excitatory amino acid antagonists and antiischemic agents, useful in the treatment of cerebral ischemia resulting from stroke | K AND K BIOSCIENCE, INC. (US) | 2006-03-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060058357-A1 | Delta2-1,2,3-triazoline anticonvulsants and their active metabolite analogues, the aminoalkylpyridines, are excitatory amino acid antagonists and antiischemic agents, useful in the treatment of cerebral ischemia resulting from stroke | SIGMAR1, GRM1, GRIN2C | CYP19A1 4624/4885KIF11 3865/4885CYP11B1 2146/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.