Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 18/20 | 0.46 |
| ▸ | MRGPRX2 | Q96LB1 | 1/20 | 0.45 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.45 |
| ▸ | SLC34A2 | O95436 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL46801 | 1.00 | CCR2 (0.46) | CCR2MRGPRX2MRGPRX1SLC34A2 | |
| SCHEMBL46454 | 1.00 | CCR2 (0.46) | CCR2MRGPRX2MRGPRX1SLC34A2 | |
| Trifluoroacetic Acid SCHEMBL18040405 | 0.98 | CCR2 (0.44) | CCR2MRGPRX2MRGPRX1SLC34A2 | |
| SCHEMBL5999504 | 0.96 | MRGPRX2 (0.43) | CCR2MRGPRX2MRGPRX1SLC34A2 | |
| SCHEMBL46665 | 0.92 | CCR2 (0.48) | CCR2MRGPRX2MRGPRX1SLC34A2 | |
| SCHEMBL46468 | 0.92 | CCR2 (0.48) | CCR2MRGPRX2MRGPRX1SLC34A2 | |
| SCHEMBL39817 | 0.88 | SLC34A2 (0.43) | SLC34A2 | |
| SCHEMBL10274674 | 0.88 | SLC34A2 (0.46) | CCR2MRGPRX2MRGPRX1SLC34A2 | |
| SCHEMBL46720 | 0.87 | SLC34A2 (0.42) | SLC34A2 | |
| SCHEMBL46689 | 0.86 | MRGPRX2 (0.46) | CCR2MRGPRX2MRGPRX1SLC34A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012054110-A2 | COMPOUNDS AND METHODS FOR INHIBITING PHOSPHATE TRANSPORT | ARDELYX, INC. (US) | 2012-04-26 | — | — | WO | disclosed |