Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | GUSB | P08236 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MPI | P34949 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21113697 | 0.73 | BRD4 (0.40) | KDM4ELMNAMAPT | |
| SCHEMBL6002128 | 0.73 | ALDH1A1 (0.45) | POLBMAOA | |
| SCHEMBL5527650 | 0.72 | ATM (0.51) | — | |
| SCHEMBL5527648 | 0.72 | ATM (0.51) | — | |
| SCHEMBL12190592 | 0.72 | RRM2 (0.48) | POLBKDM4EL3MBTL1GAAMAOB | |
| SCHEMBL31192684 | 0.72 | ATM (0.51) | — | |
| SCHEMBL21113703 | 0.72 | BRD4 (0.34) | POLB | |
| SCHEMBL21113675 | 0.72 | CYP2C9 (0.39) | KDM4EGAASMN1; SMN2MAPT | |
| SCHEMBL21113679 | 0.71 | BRD4 (0.45) | POLBKDM4EGAASMN1; SMN2LMNA | |
| SCHEMBL21113641 | 0.71 | KCNH2 (0.37) | SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1734939-A1 | ANTI-PARASITIC COMPOUNDS AND METHODS OF THEIR USE | The Regents of The University of California (US) | 2006-12-27 | — | — | EP | disclosed |
| WO-2005087211-A1 | ANTI-PARASITIC COMPOUNDS AND METHODS OF THEIR USE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2005-09-22 | — | — | WO | disclosed |