Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.51 |
| ▸ | CTSK | P43235 | 1/20 | 0.51 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | CTSL | P07711 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5527648 | 1.00 | ATM (0.51) | ATMMETTL3CTSKHSP90AA1ALDH1A1 | |
| SCHEMBL31192684 | 1.00 | ATM (0.51) | ATMMETTL3CTSKHSP90AA1ALDH1A1 | |
| SCHEMBL13826734 | 0.92 | ATM (0.59) | ATMMETTL3CTSKHSP90AA1CTSL | |
| SCHEMBL29010741 | 0.92 | ATM (0.59) | ATMMETTL3CTSKHSP90AA1CTSL | |
| SCHEMBL15501263 | 0.88 | ATM (0.54) | ATMMETTL3CTSKHSP90AA1CTSL | |
| SCHEMBL29010740 | 0.84 | TOP2A (0.61) | HSP90AA1ALDH1A1 | |
| SCHEMBL13826733 | 0.82 | LMNA (0.59) | HSP90AA1ALDH1A1 | |
| SCHEMBL15501375 | 0.78 | LMNA (0.54) | HSP90AA1ALDH1A1 | |
| SCHEMBL6743847 | 0.76 | HSP90AA1 (0.49) | ATMMETTL3CTSKHSP90AA1ALDH1A1 | |
| SCHEMBL6743841 | 0.76 | HSP90AA1 (0.49) | ATMMETTL3CTSKHSP90AA1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109651414-B | Indium compound with 2, 6-diacetyl pyridine thiosemicarbazone as ligand and synthetic method and application thereof | 广西师范大学 | 2020-12-22 | — | — | CN | claimed |
| CN-109651414-A | It is a kind of using 2,6-diacetylpyridine thiosemicarbazones as the indium compound of ligand and its synthetic method and application | 广西师范大学 | 2019-04-19 | — | — | CN | claimed |
| CN-109651414-B | Indium compound with 2, 6-diacetyl pyridine thiosemicarbazone as ligand and synthetic method and application thereof | 广西师范大学 | 2020-12-22 | — | — | CN | disclosed |
| CN-109651414-B | Indium compound with 2, 6-diacetyl pyridine thiosemicarbazone as ligand and synthetic method and application thereof | 广西师范大学 | 2020-12-22 | — | — | CN | disclosed |
| CN-109651414-B | Indium compound with 2, 6-diacetyl pyridine thiosemicarbazone as ligand and synthetic method and application thereof | 广西师范大学 | 2020-12-22 | — | — | CN | disclosed |
| CN-109651414-A | It is a kind of using 2,6-diacetylpyridine thiosemicarbazones as the indium compound of ligand and its synthetic method and application | 广西师范大学 | 2019-04-19 | — | — | CN | disclosed |
| CN-109651414-A | It is a kind of using 2,6-diacetylpyridine thiosemicarbazones as the indium compound of ligand and its synthetic method and application | 广西师范大学 | 2019-04-19 | — | — | CN | disclosed |
| CN-109651414-A | It is a kind of using 2,6-diacetylpyridine thiosemicarbazones as the indium compound of ligand and its synthetic method and application | 广西师范大学 | 2019-04-19 | — | — | CN | disclosed |
| US-20070197495-A1 | ANTI-PARASITIC COMPOUNDS AND METHODS OF THEIR USE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2007-08-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070197495-A1 | ANTI-PARASITIC COMPOUNDS AND METHODS OF THEIR USE | CYP51A1, TUBA3C, PIGO | ATM 4843/4885METTL3 4301/4885CTSK 107/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.