Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 9/20 | 0.72 |
| ▸ | CNR1 | P21554 | 3/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | PSEN1 | P49768 | 7/20 | 0.56 |
| ▸ | PSEN2 | P49810 | 7/20 | 0.56 |
| ▸ | APH1B | Q8WW43 | 7/20 | 0.56 |
| ▸ | NCSTN | Q92542 | 7/20 | 0.56 |
| ▸ | APH1A | Q96BI3 | 7/20 | 0.56 |
| ▸ | PSENEN | Q9NZ42 | 7/20 | 0.56 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL599985 | 0.90 | CNR2 (0.71) | CNR2CNR1KDM4EHSD17B10PSEN1 | |
| SCHEMBL601586 | 0.87 | CNR2 (0.72) | CNR2CNR1KDM4EHSD17B10PSEN1 | |
| SCHEMBL23148486 | 0.87 | KDM4E (0.57) | CNR2CNR1ALDH1A1HPGDKDM4E | |
| SCHEMBL29677813 | 0.85 | ALDH1A1 (0.68) | CNR2CNR1ALDH1A1HPGDKDM4E | |
| SCHEMBL2804157 | 0.85 | ALDH1A1 (0.68) | CNR2CNR1ALDH1A1HPGDKDM4E | |
| SCHEMBL600020 | 0.84 | CNR2 (0.85) | CNR2CNR1PSEN1PSEN2APH1B | |
| SCHEMBL597697 | 0.84 | CNR2 (1.00) | CNR2CNR1 | |
| SCHEMBL600012 | 0.83 | ALDH1A1 (0.82) | CNR2CNR1ALDH1A1HPGDKDM4E | |
| SCHEMBL599853 | 0.82 | CNR2 (0.82) | CNR2CNR1 | |
| SCHEMBL601808 | 0.82 | CNR2 (0.59) | CNR2CNR1ALDH1A1HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220380367-A1 | MODIFIED CARBAZOLES AS THERAPEUTIC AGENTS | THE UNIVERSITY OF MONTANA | 2022-12-01 | — | — | US | disclosed |
| US-11420967-B2 | Modified carbazoles as therapeutic agents | UNIVERSITY OF WASHINGTON (US) | 2022-08-23 | — | — | US | disclosed |
| US-20210094949-A1 | MODIFIED CARBAZOLES AS THERAPEUTIC AGENTS | THE UNIVERSITY OF MONTANA | 2021-04-01 | — | — | US | disclosed |
| US-20170096426-A1 | Novel Tricyclic Modulators of Cannabinoid Receptors | THE UNIV OF MONTANA (US) | 2017-04-06 | — | — | US | disclosed |
| US-20170096426-A1 | Novel Tricyclic Modulators of Cannabinoid Receptors | THE UNIV OF MONTANA (US) | 2017-04-06 | — | — | US | disclosed |
| US-20170096426-A1 | Novel Tricyclic Modulators of Cannabinoid Receptors | THE UNIV OF MONTANA (US) | 2017-04-06 | — | — | US | disclosed |
| US-20120039804-A1 | Novel Tricyclic Modulators of Cannabinoid Receptors | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2012-02-16 | — | — | US | disclosed |
| US-20120039804-A1 | Novel Tricyclic Modulators of Cannabinoid Receptors | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2012-02-16 | — | — | US | disclosed |
| US-20120039804-A1 | Novel Tricyclic Modulators of Cannabinoid Receptors | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2012-02-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220380367-A1 | MODIFIED CARBAZOLES AS THERAPEUTIC AGENTS | TUBB3, TUBB1, TUBA1C | CNR2 2189/4885CNR1 2023/4885ALDH1A1 3841/4885 |
| US-20210094949-A1 | MODIFIED CARBAZOLES AS THERAPEUTIC AGENTS | TUBB3, TUBB1, TUBA1C | CNR2 2189/4885CNR1 2023/4885ALDH1A1 3841/4885 |
| US-20120039804-A1 | Novel Tricyclic Modulators of Cannabinoid Receptors | CNR1, CNR2, OPRL1 | CNR2 2/4885CNR1 1/4885ALDH1A1 4037/4885 |
| US-20170096426-A1 | Novel Tricyclic Modulators of Cannabinoid Receptors | CNR1, CNR2, OPRL1 | CNR2 2/4885CNR1 1/4885ALDH1A1 4037/4885 |
| US-11420967-B2 | Modified carbazoles as therapeutic agents | TUBB3, TUBB1, TUBA1C | CNR2 2189/4885CNR1 2023/4885ALDH1A1 3841/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.