Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SETD7 | Q8WTS6 | 3/20 | 0.49 |
| ▸ | TCF4 | P15884 | 1/20 | 0.48 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.43 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6000763 | 1.00 | SETD7 (0.49) | SETD7TCF4CTNNB1ALDH1A1ADRA2A | |
| Hydrochloric Acid SCHEMBL7212429 | 0.99 | SETD7 (0.48) | SETD7TCF4CTNNB1ALDH1A1ADRA2A | |
| Hydrochloric Acid SCHEMBL7218787 | 0.99 | SETD7 (0.48) | SETD7TCF4CTNNB1ALDH1A1ADRA2A | |
| SCHEMBL7306999 | 0.88 | TCF4 (0.48) | SETD7TCF4CTNNB1ALDH1A1MAPK1 | |
| SCHEMBL7306992 | 0.88 | TCF4 (0.48) | SETD7TCF4CTNNB1ALDH1A1MAPK1 | |
| SCHEMBL7306397 | 0.86 | TCF4 (0.47) | SETD7TCF4CTNNB1ALDH1A1ADRA2A | |
| SCHEMBL7310123 | 0.86 | TCF4 (0.47) | SETD7TCF4CTNNB1ALDH1A1ADRA2A | |
| SCHEMBL7433819 | 0.85 | SETD7 (0.54) | SETD7ALDH1A1ADRA2AADRA2CSLC6A4 | |
| SCHEMBL7436166 | 0.85 | SETD7 (0.54) | SETD7ALDH1A1ADRA2AADRA2CSLC6A4 | |
| SCHEMBL7306260 | 0.85 | SETD7 (0.59) | SETD7ALDH1A1ADRA2AADRA2CSLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5250681-A | Piperidine derivatives and hypotensives containing the same | AJINOMOTO CO., INC. (JP) | 1993-10-05 | — | — | US | claimed |
| JP-6065202-A | — | — | None | — | — | JP | disclosed |
| JP-4261154-A | — | — | None | — | — | JP | disclosed |
| US-20060140991-A1 | Pharmaceutical preparations having an improved solubility | AJINOMOTO CO. INC (JP) | 2006-06-29 | — | — | US | disclosed |
| EP-1661556-A1 | MEDICINAL PREPARATION HAVING IMPROVED DISSOLUTION PROPERTIES | Ajinomoto Co., Inc. (JP) | 2006-05-31 | — | — | EP | disclosed |
| EP-0530016-B1 | Piperidine derivative and pharmaceutical composition containing it | AJINOMOTO KK (JP) | 1995-08-02 | — | — | EP | disclosed |
| JP-H0665202-A | PIPERIDINE DERIVATIVE AND HYPOTENSOR CONTAINING SAME | AJINOMOTO CO INC | 1994-03-08 | — | — | JP | disclosed |
| EP-0530016-A2 | Piperidine derivative and pharmaceutical composition containing it | Ajinomoto Co., Inc. (JP) | 1993-03-03 | — | — | EP | disclosed |
| JP-H04261154-A | PIPERIDINE DERIVATIVE AND ANTIHYPERTENSIVE AGENT CONTAINING THE SAME | AJINOMOTO CO INC | 1992-09-17 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060140991-A1 | Pharmaceutical preparations having an improved solubility | SI, LSS, PDE8B | SETD7 627/4885TCF4 3949/4885CTNNB1 4781/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.