SCHEMBL600082

SCHEMBL600082

O=C(O)/C=C/c1cccs1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 1/20 1.00
ABCG2 Q9UNQ0 2/20 0.59
SMN1; SMN2 Q16637 5/20 0.57
ALDH1A1 P00352 4/20 0.57
LMNA P02545 3/20 0.57
MAPT P10636 3/20 0.57
RAB9A P51151 4/20 0.54
MEN1 O00255 3/20 0.54
KMT2A Q03164 3/20 0.54
KDM4E B2RXH2 2/20 0.54
NPC1 O15118 2/20 0.54
PSMD14 O00487 1/20 0.54
TP53 P04637 1/20 0.54
GLA P06280 1/20 0.54
HTT P42858 1/20 0.54
HPGD P15428 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL143282 1.00 HCAR2 (1.00) HCAR2ABCG2SMN1; SMN2ALDH1A1LMNA
Hydrochloric Acid SCHEMBL9874572 0.98 HCAR2 (0.96) HCAR2ABCG2SMN1; SMN2ALDH1A1LMNA
SCHEMBL4212112 0.98 HCAR2 (0.96) HCAR2ABCG2SMN1; SMN2ALDH1A1LMNA
SCHEMBL31591277 0.93 HCAR2 (0.86) HCAR2ABCG2SMN1; SMN2ALDH1A1LMNA
SCHEMBL9117065 0.86 HCAR2 (0.76) HCAR2ABCG2SMN1; SMN2ALDH1A1LMNA
SCHEMBL5598744 0.85 HCAR2 (0.74) HCAR2ABCG2SMN1; SMN2ALDH1A1LMNA
SCHEMBL5598741 0.85 HCAR2 (0.74) HCAR2ABCG2SMN1; SMN2ALDH1A1LMNA
SCHEMBL9580713 0.85 HCAR2 (0.73) HCAR2ABCG2SMN1; SMN2ALDH1A1LMNA
SCHEMBL10332830 0.84 HCAR2 (0.72) HCAR2ABCG2SMN1; SMN2ALDH1A1LMNA
SCHEMBL10332828 0.84 HCAR2 (0.72) HCAR2ABCG2SMN1; SMN2ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 637 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115433928-A Chemical silver plating liquid medicine and chemical silver plating method for 5G high-frequency circuit board 深圳市板明科技股份有限公司 2022-12-06 CN claimed
CN-115058762-B Tin settling agent for electrotinning process and use method thereof 深圳市板明科技股份有限公司 2022-11-08 CN claimed
CN-115058762-A Tin settling agent for electrotinning process and use method thereof 深圳市板明科技股份有限公司 2022-09-16 CN claimed
CN-113912769-A Temperature-resistant salt-tolerant gel foam system and preparation method and application thereof 中国石油化工股份有限公司 2022-01-11 CN claimed
US-10072043-B2 Inhibitors of protein tyrosine phosphatases INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) 2018-09-11 US claimed
EP-2969029-B1 USE OF COSMETICALLY OR DERMATOLOGICALLY SAFE SUBSTITUTED MICHAEL ACCEPTORS FOR THE PREVENTION, REDUCTION OR PROPHYLAXIS OF THE TYROSINASE ACTIVITY OF THE HUMAN SKIN AND/OR THE LIGHTENING OF THE HUMAN SKIN BEIERSDORF AG (DE) 2018-07-11 EP claimed
US-9999678-B2 C6-C18-acylated derivative of hyaluronic acid and method of preparation thereof CONTIPRO A.S. (CZ) 2018-06-19 US claimed
EP-2934592-B1 C6-C18-ACYLATED DERIVATIVE OF HYALURONIC ACID, METHOD OF PREPARATION THEREOF, NANOMICELLAR COMPOSITION ON ITS BASIS, METHOD OF PREPARATION THEREOF AND METHOD OF PREPARATION STABILIZED NANOMICELLAR COMPOSITION, AND USE THEREOF CONTIPRO AS (CZ) 2018-05-16 EP claimed
US-20160176922-A1 INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES Indiana University Research and Technology Corpora tion (US) 2016-06-23 US claimed
EP-2969029-A2 USE OF COSMETICALLY OR DERMATOLOGICALLY SAFE SUBSTITUTED MICHAEL ACCEPTORS FOR THE PREVENTION, REDUCTION OR PROPHYLAXIS OF THE TYROSINASE ACTIVITY OF THE HUMAN SKIN AND/OR THE LIGHTENING OF THE HUMAN SKIN Beiersdorf AG (DE) 2016-01-20 EP claimed
US-5843979-A Transdermal treatment with mast cell degranulating agents for drug-induced hypersensitivity BRISTOL-MYERS SQUIBB COMPANY (US) 1998-12-01 US claimed
WO-1998032016-A2 A CYANIDE-FREE LYTIC REAGENT COMPOSITION AND METHOD FOR HEMOGLOBIN AND CELL ANALYSIS COULTER INTERNATIONAL CORP. (US) 1998-07-23 WO claimed
US-5763280-A LYSING WITH A SURFACTANT; COMBINING WITH LIGAND TO FORM A STABLE CHROMOGEN WITH HEMOGLOBIN COULTER INTERNATIONAL CORP. (US) 1998-06-09 US claimed
EP-0802782-A4 PROPHYLACTIC AND THERAPEUTIC TREATMENT OF SKIN SENSITIZATION AND IRRITATION BRISTOL MYERS SQUIBB CO (US) 1998-04-01 EP claimed
WO-1997047355-A1 REDUCTION OF SKIN SENSITIZATION IN ELECTROTRANSPORT DRUG DELIVERY ALZA CORPORATION (US) 1997-12-18 WO claimed
US-5686100-A Prophylactic and therapeutic treatment of skin sensitization and irritation E.R. SQUIBB & SONS, INC. (US) 1997-11-11 US claimed
EP-0802782-A1 PROPHYLACTIC AND THERAPEUTIC TREATMENT OF SKIN SENSITIZATION AND IRRITATION BRISTOL-MYERS SQUIBB COMPANY (US) 1997-10-29 EP claimed
WO-1996015771-A1 PROPHYLACTIC AND THERAPEUTIC TREATMENT OF SKIN SENSITIZATION AND IRRITATION BRISTOL-MYERS SQUIBB COMPANY (US) 1996-05-30 WO claimed
EP-0612525-A1 Transdermal treatment with mast cell degranulating agents for drug-induced hypersensitivity BRISTOL-MYERS SQUIBB COMPANY (US) 1994-08-31 EP claimed
EP-0440329-A1 S-substituted carbonyl substituted betathioacrylamide biocides and fungicides ROHM AND HAAS COMPANY (US) 1991-08-07 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10072043-B2 Inhibitors of protein tyrosine phosphatases PTPRCAP, PTPRF, PTPRS HCAR2 4789/4885ABCG2 999/4885SMN1; SMN2 4271/4885
US-20160176922-A1 INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES PTPRCAP, PTPRF, PTPRS HCAR2 4789/4885ABCG2 999/4885SMN1; SMN2 4271/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.