SCHEMBL143282

SCHEMBL143282

O=C(O)C=Cc1cccs1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 1/20 1.00
ABCG2 Q9UNQ0 2/20 0.59
SMN1; SMN2 Q16637 5/20 0.57
ALDH1A1 P00352 4/20 0.57
LMNA P02545 3/20 0.57
MAPT P10636 3/20 0.57
RAB9A P51151 4/20 0.54
MEN1 O00255 3/20 0.54
KMT2A Q03164 3/20 0.54
KDM4E B2RXH2 2/20 0.54
NPC1 O15118 2/20 0.54
PSMD14 O00487 1/20 0.54
TP53 P04637 1/20 0.54
GLA P06280 1/20 0.54
HTT P42858 1/20 0.54
HPGD P15428 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL600082 1.00 HCAR2 (1.00) HCAR2ABCG2SMN1; SMN2ALDH1A1LMNA
Hydrochloric Acid SCHEMBL9874572 0.98 HCAR2 (0.96) HCAR2ABCG2SMN1; SMN2ALDH1A1LMNA
SCHEMBL4212112 0.98 HCAR2 (0.96) HCAR2ABCG2SMN1; SMN2ALDH1A1LMNA
SCHEMBL31591277 0.93 HCAR2 (0.86) HCAR2ABCG2SMN1; SMN2ALDH1A1LMNA
SCHEMBL9117065 0.86 HCAR2 (0.76) HCAR2ABCG2SMN1; SMN2ALDH1A1LMNA
SCHEMBL5598744 0.85 HCAR2 (0.74) HCAR2ABCG2SMN1; SMN2ALDH1A1LMNA
SCHEMBL5598741 0.85 HCAR2 (0.74) HCAR2ABCG2SMN1; SMN2ALDH1A1LMNA
SCHEMBL9580713 0.85 HCAR2 (0.73) HCAR2ABCG2SMN1; SMN2ALDH1A1LMNA
SCHEMBL10332830 0.84 HCAR2 (0.72) HCAR2ABCG2SMN1; SMN2ALDH1A1LMNA
SCHEMBL10332828 0.84 HCAR2 (0.72) HCAR2ABCG2SMN1; SMN2ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1362 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122058334-A Self-sensing artificial muscle, deformation sensing method, preparation method and miniature grabbing device 江苏大学 2026-05-19 CN claimed
US-20260133354-A1 STRUCTURED TRANSFER ARTICLES AND ARTICLES, AND METHODS OF MAKING STRUCTURED ARTICLES 3M INNOVATIVE PROPERTIES CO (US) 2026-05-14 US claimed
CN-122028974-A Ribonucleic acid-based microcapsules 弗门尼舍有限公司 2026-05-12 CN claimed
EP-4724261-A1 METHODS AND SYSTEMS FOR FABRICATING THREE-DIMENSIONAL OBJECTS BY ADDITIVE MANUFACTURING University Of Tasmania (AU) 2026-04-15 EP claimed
US-20260034034-A1 COMPOSITE MICROCAPSULES FIRMENICH & CIE (CH) 2026-02-05 US claimed
EP-4683684-A1 POST-PROCESSING OF BIOLOGICAL SCAFFOLDS Lung Biotechnology PBC (US) 2026-01-28 EP claimed
US-20260008933-A1 UNIFORM UV-CURABLE COATINGS FOR 3D-PRINTED ORTHODONTIC DEVICES AND METHODS FOR PREPARING THE SAME ALIGN TECHNOLOGY INC (US) 2026-01-08 US claimed
US-20250382499-A1 WATERBORNE COATING FORMULATION WITH POLYHEDRAL OLIGOMERIC SILSESQUIOXANE, SYNTHETIC METHOD AND APPLICATION THEREOF NANO & ADVANCED MATERIALS INST LTD (HK) 2025-12-18 US claimed
EP-4661890-A1 PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS Purdue Research Foundation (US) 2025-12-17 EP claimed
EP-4639242-A1 STRUCTURED TRANSFER ARTICLES AND ARTICLES, AND METHODS OF MAKING STRUCTURED ARTICLES 3M Innovative Properties Company (US) 2025-10-29 EP claimed
WO-1997047355-A1 REDUCTION OF SKIN SENSITIZATION IN ELECTROTRANSPORT DRUG DELIVERY ALZA CORPORATION (US) 1997-12-18 WO claimed
US-5686100-A Prophylactic and therapeutic treatment of skin sensitization and irritation E.R. SQUIBB & SONS, INC. (US) 1997-11-11 US claimed
EP-0802782-A1 PROPHYLACTIC AND THERAPEUTIC TREATMENT OF SKIN SENSITIZATION AND IRRITATION BRISTOL-MYERS SQUIBB COMPANY (US) 1997-10-29 EP claimed
EP-0727713-A1 Photoresist having increased sensitivity and use thereof INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 1996-08-21 EP claimed
WO-1996015771-A1 PROPHYLACTIC AND THERAPEUTIC TREATMENT OF SKIN SENSITIZATION AND IRRITATION BRISTOL-MYERS SQUIBB COMPANY (US) 1996-05-30 WO claimed
EP-0612525-A1 Transdermal treatment with mast cell degranulating agents for drug-induced hypersensitivity BRISTOL-MYERS SQUIBB COMPANY (US) 1994-08-31 EP claimed
EP-0440329-A1 S-substituted carbonyl substituted betathioacrylamide biocides and fungicides ROHM AND HAAS COMPANY (US) 1991-08-07 EP claimed
EP-0046595-B1 ACYLATED FURANYL AND THIENYL ACRYLIC ACIDS, PROCESS FOR THEIR PRODUCTION, AND PHARMACEUTICAL COMPOSITIONS MERRELL DOW PHARMACEUTICALS INC. (US) 1984-10-24 EP claimed
US-3989882-A Process for preparing an alternating copolymer of a conjugated vinyl compound and an olefinic unsaturated compound SUMITOMO CHEMICAL COMPANY, LIMITED (JA) 1976-11-02 US claimed
US-3945831-A Photosensitive resins containing a thienylacrylic acid ester or amide group FUJI PHOTO FILM CO., LTD. (JA) 1976-03-23 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260034034-A1 COMPOSITE MICROCAPSULES S100P, HAMP, PCTP HCAR2 2846/4885ABCG2 2677/4885SMN1; SMN2 4737/4885
US-20260133354-A1 STRUCTURED TRANSFER ARTICLES AND ARTICLES, AND METHODS OF MAKING STRUCTURED ARTICLES ICAM1, CD63, CDH1 HCAR2 4578/4885ABCG2 4306/4885SMN1; SMN2 918/4885
US-20260008933-A1 UNIFORM UV-CURABLE COATINGS FOR 3D-PRINTED ORTHODONTIC DEVICES AND METHODS FOR PREPARING THE SAME MAP1LC3B, MAP1LC3A, MAP1LC3C HCAR2 2531/4885ABCG2 3722/4885SMN1; SMN2 2207/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.