Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL238817 | 0.92 | MAOB (0.72) | MAOBMAOA | |
| SCHEMBL29545160 | 0.92 | MAOB (0.72) | MAOBMAOA | |
| SCHEMBL6588324 | 0.90 | MAOB (0.70) | MAOBMAOA | |
| SCHEMBL1040338 | 0.87 | MAOB (0.70) | MAOBMAOA | |
| SCHEMBL2842062 | 0.86 | MAOB (0.80) | MAOBMAOA | |
| SCHEMBL6585388 | 0.85 | MAOB (0.60) | MAOBMAOA | |
| SCHEMBL6585582 | 0.85 | MAOB (0.67) | MAOBMAOA | |
| SCHEMBL29935397 | 0.81 | MAOB (0.72) | MAOBMAOA | |
| SCHEMBL6585538 | 0.81 | MAOB (0.68) | MAOBMAOA | |
| SCHEMBL28843241 | 0.81 | MAOB (0.72) | MAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060234997-A1 | Tetrahydro-pyridoazepin-8-ones and related compounds for the treatment of schizophrenia | WARNER-LAMBERT COMPANY LLC | 2006-10-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060234997-A1 | Tetrahydro-pyridoazepin-8-ones and related compounds for the treatment of schizophrenia | PTGDR, GRIN2A, PTGDR2 | MAOB 13/4885MAOA 19/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.