Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNRHR | P30968 | 19/20 | 0.86 |
| ▸ | HTR1A | P08908 | 3/20 | 0.68 |
| ▸ | HTR1D | P28221 | 1/20 | 0.51 |
| ▸ | HTR1B | P28222 | 1/20 | 0.51 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5505179 | 0.94 | GNRHR (0.84) | GNRHRHTR1AHTR1DHTR1BDRD2 | |
| SCHEMBL5508562 | 0.90 | GNRHR (0.81) | GNRHRHTR1AHTR1DHTR1BDRD2 | |
| SCHEMBL6001440 | 0.89 | GNRHR (0.82) | GNRHRHTR1AHTR1DHTR1BDRD2 | |
| SCHEMBL5509052 | 0.88 | GNRHR (0.87) | GNRHRHTR1AHTR1DHTR1BDRD2 | |
| SCHEMBL5512022 | 0.88 | GNRHR (0.79) | GNRHRHTR1AHTR1DHTR1BDRD2 | |
| SCHEMBL5999613 | 0.88 | GNRHR (1.00) | GNRHRHTR1AHTR1DHTR1BDRD2 | |
| SCHEMBL6001207 | 0.88 | GNRHR (0.79) | GNRHRHTR1AHTR1DHTR1BDRD2 | |
| SCHEMBL5509610 | 0.88 | GNRHR (0.77) | GNRHRHTR1AHTR1DHTR1BDRD2 | |
| SCHEMBL5514480 | 0.87 | GNRHR (0.82) | GNRHRHTR1AHTR1DHTR1BDRD2 | |
| SCHEMBL5509716 | 0.87 | GNRHR (0.82) | GNRHRHTR1AHTR1DHTR1BDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060111355-A1 | Gonadotropin releasing hormone receptor antagonists | WYETH (US) | 2006-05-25 | — | — | US | claimed |
| US-20060111355-A1 | Gonadotropin releasing hormone receptor antagonists | WYETH (US) | 2006-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060111355-A1 | Gonadotropin releasing hormone receptor antagonists | GNRHR, LHCGR, GHRHR | GNRHR 1/4885HTR1A 339/4885HTR1D 489/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.