SCHEMBL600138

SCHEMBL600138

C=CC(=O)OC[Si](C)(C)C

nearest known ligand 0.50

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 8/20 0.50
HPGD P15428 1/20 0.48
ALDH1A1 P00352 6/20 0.48
TP53 P04637 3/20 0.48
HIF1A Q16665 3/20 0.48
CYP3A4 P08684 2/20 0.48
HSD17B10 Q99714 1/20 0.48
MAPK1 P28482 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
THRB P10828 4/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2403942 1.00 TSHR (0.50) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL9411504 0.86 TSHR (0.50) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL1011852 0.84 TSHR (0.48) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL8420105 0.84 TSHR (0.54) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL5813562 0.82 TSHR (0.43) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL14559751 0.82 TSHR (0.47) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL7782623 0.82 TSHR (0.47) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL332972 0.82 TSHR (0.47) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL107384 0.80 TSHR (0.45) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL2310688 0.80 TSHR (0.45) TSHRHPGDALDH1A1TP53HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 207 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12600820-B2 Photocurable composition with high silicon content CANON KABUSHIKI KAISHA (JP) 2026-04-14 US claimed
US-20250368802-A1 PHOTOCURABLE COMPOSITION WITH HIGH SILICON CONTENT AND HIGH STABILITY CANON KK (JP) 2025-12-04 US claimed
CN-119954476-A Solid waste-based filling material for improving leaching rate of heavy metals and preparation method thereof 北京科技大学 2025-05-09 CN claimed
WO-2025075506-A1 COATED POROUS MEDIA, METHOD OF MANUFACTURING A COATED POROUS MEDIA AND THE USE OF SUCH COATED POROUS MEDIA TECHNISCHE UNIVERSITEIT EINDHOVEN (NL) 2025-04-10 WO claimed
CN-119638357-A Solid waste-based high-fluidity filling material and preparation method thereof 北京科技大学 2025-03-18 CN claimed
US-20240199816-A1 PHOTOCURABLE COMPOSITION WITH HIGH SILICON CONTENT CANON KABUSHIKI KAISHA (JP) 2024-06-20 US claimed
WO-2024123531-A1 PHOTOCURABLE COMPOSITION WITH HIGH SILICON CONTENT CANON KABUSHIKI KAISHA (JP) 2024-06-13 WO claimed
EP-3861039-B1 HYDROGEL COMPOSITIONS OPHTALMIC CIE (FR) 2023-11-01 EP claimed
CN-111871071-B High-temperature-resistant and corrosion-resistant microporous membrane material for processing mask filter layer 吉祥三宝高科纺织有限公司 2022-02-15 CN claimed
US-20210332174-A1 HYDROGEL COMPOSITIONS OPHTALMIC COMPAGNIE (FR) 2021-10-28 US claimed
EP-3861039-A1 HYDROGEL COMPOSITIONS Ophtalmic Compagnie (FR) 2021-08-11 EP claimed
CN-113166340-A Hydrogel composition 眼科公司 2021-07-23 CN claimed
CN-109594420-B Release paper for floor leather production and preparation method thereof 浙江博力莫新材料科技有限公司 2021-04-23 CN claimed
CN-111871071-A High-temperature-resistant and corrosion-resistant microporous membrane material for processing mask filter layer 吉祥三宝高科纺织有限公司 2020-11-03 CN claimed
WO-2020070423-A1 HYDROGEL COMPOSITIONS OPHTALMIC COMPAGNIE (FR) 2020-04-09 WO claimed
CN-110283273-A A kind of high moisturizing flexible hydrophilic silicone-hydrogel and preparation method thereof 甘肃天后光学科技有限公司 2019-09-27 CN claimed
CN-109594420-A A kind of release paper and preparation method thereof for flooring laminate production 浙江博力莫新材料科技有限公司 2019-04-09 CN claimed
WO-2018017570-A1 A HAIR STRAIGHTENING AND STYLING COMPOSITION, PROCESS FOR PREPARING THE SAME AND METHOD OF USE THEREOF ISP INVESTMENTS LLC (US) 2018-01-25 WO claimed
US-7122482-B2 Methods for fabricating patterned features utilizing imprint lithography MOLECULAR IMPRINTS, INC. (US) 2006-10-17 US claimed
US-20050100830-A1 Methods for fabricating patterned features utilizing imprint lithography MOLECULAR IMPRINTS, INC. (US) 2005-05-12 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12600820-B2 Photocurable composition with high silicon content BIRC2, ACP1, IRS1 TSHR 4173/4885HPGD 4675/4885ALDH1A1 3351/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.