Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 8/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | TP53 | P04637 | 3/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2403942 | 0.84 | TSHR (0.50) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL9411504 | 0.84 | TSHR (0.50) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL600138 | 0.84 | TSHR (0.50) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL1011852 | 0.82 | TSHR (0.48) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL7782623 | 0.80 | TSHR (0.47) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL332972 | 0.80 | TSHR (0.47) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL14559751 | 0.80 | TSHR (0.47) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL2310688 | 0.78 | TSHR (0.45) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL107384 | 0.78 | TSHR (0.45) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL5069823 | 0.78 | TSHR (0.45) | TSHRHPGDALDH1A1TP53HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2490663-B1 | SILICONE COMPOSITIONS COMPRISING A SWOLLEN SILICONE GEL | DOW CORNING (US) | 2017-09-20 | — | — | EP | claimed |
| EP-2536786-B1 | SURFACE-MODIFIED HYDROGELS AND HYDROGEL MICROPARTICLES | DOW CORNING (US) | 2015-12-30 | — | — | EP | claimed |
| EP-0315954-B1 | Pattern-forming material and pattern formation method | TORAY SILICONE CO (JP) | 1995-11-22 | — | — | EP | claimed |
| US-4985342-A | Semiconductors, Integrated Circuits | TORAY SILICONE COMPANY, LTD. (JP) | 1991-01-15 | — | — | US | claimed |
| EP-0315954-A2 | Pattern-forming material and pattern formation method | TORAY SILICONE COMPANY, LIMITED (JP) | 1989-05-17 | — | — | EP | claimed |
| EP-0487291-B1 | Photocurable silicon composition, and method of making same | LOCTITE CORP (US) | 1999-09-29 | — | — | EP | disclosed |
| EP-0315954-B1 | Pattern-forming material and pattern formation method | TORAY SILICONE CO (JP) | 1995-11-22 | — | — | EP | disclosed |
| US-5461173-A | Fluorine-containing organosilicon compound and its manufacture | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1995-10-24 | — | — | US | disclosed |
| US-5348986-A | Polysiloxanes capped with mixture of curable groups, gels, acrylated polymers | LOCTITE CORPORATION (US) | 1994-09-20 | — | — | US | disclosed |
| US-5182315-A | Endcapping | LOCTITE CORPORATION (US) | 1993-01-26 | — | — | US | disclosed |
| EP-0487291-A2 | Photocurable silicon composition, and method of making same | LOCTITE CORPORATION (US) | 1992-05-27 | — | — | EP | disclosed |
| US-4985342-A | Semiconductors, Integrated Circuits | TORAY SILICONE COMPANY, LTD. (JP) | 1991-01-15 | — | — | US | disclosed |
| EP-0315954-A2 | Pattern-forming material and pattern formation method | TORAY SILICONE COMPANY, LIMITED (JP) | 1989-05-17 | — | — | EP | disclosed |