Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | LMNA | P02545 | 6/20 | 0.51 |
| ▸ | HPGD | P15428 | 5/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.51 |
| ▸ | GBA1 | P04062 | 11/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.50 |
| ▸ | MAPT | P10636 | 7/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | PDE5A | O76074 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6001185 | 0.83 | MEN1 (0.37) | ALDH1A1LMNAHPGDL3MBTL1GBA1 | |
| SCHEMBL6001916 | 0.81 | MEN1 (0.43) | ALDH1A1LMNAHPGDL3MBTL1GBA1 | |
| SCHEMBL6001175 | 0.80 | PDE5A (0.48) | ALDH1A1LMNAHPGDL3MBTL1GBA1 | |
| Hydrochloric Acid SCHEMBL5358708 | 0.78 | LMNA (0.35) | ALDH1A1LMNAHPGDL3MBTL1GBA1 | |
| Hydrochloric Acid SCHEMBL5368590 | 0.75 | LMNA (0.34) | ALDH1A1LMNAHPGDL3MBTL1GBA1 | |
| SCHEMBL6001187 | 0.70 | TDP1 (0.70) | ALDH1A1LMNAHPGDL3MBTL1GBA1 | |
| SCHEMBL14323090 | 0.70 | PDE5A (0.34) | MAPTPDE5APOLBNPSR1 | |
| SCHEMBL4904331 | 0.70 | SMN1; SMN2 (0.41) | ALDH1A1LMNAHPGDL3MBTL1KDM4E | |
| SCHEMBL6001211 | 0.67 | MAPT (0.40) | ALDH1A1HPGDKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL3639827 | 0.67 | RPS6KB2 (0.32) | ALDH1A1KDM4ESMN1; SMN2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060128702-A1 | Heterocyclic and bicyclic compounds, compositions and methods | REDDY US THERAPEUTICS, INC. | 2006-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060128702-A1 | Heterocyclic and bicyclic compounds, compositions and methods | HPSE, ENGASE, UGCG | ALDH1A1 2033/4885LMNA 706/4885HPGD 189/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.