Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 6/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.43 |
| ▸ | USP2 | O75604 | 2/20 | 0.43 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6001211 | 0.83 | MAPT (0.40) | MAPTPOLBNPSR1HSD17B10USP2 | |
| SCHEMBL6001970 | 0.81 | CYP19A1 (0.45) | MAPTNPSR1LMNAHSD17B10USP2 | |
| SCHEMBL6001383 | 0.80 | ALDH1A1 (0.51) | PDE5AMAPTPOLBNPSR1LMNA | |
| Hydrochloric Acid SCHEMBL5369760 | 0.75 | PDE5A (0.36) | PDE5ACYP1A2CYP3A4CYP2C9MAPT | |
| SCHEMBL14323090 | 0.71 | PDE5A (0.34) | PDE5ACYP1A2CYP3A4CYP2C9MAPT | |
| SCHEMBL4904331 | 0.71 | SMN1; SMN2 (0.41) | MAPTPOLBNPSR1LMNAUSP2 | |
| SCHEMBL1083856 | 0.71 | CYP2D6 (0.74) | PDE5ACYP1A2CYP3A4CYP2C9MAPT | |
| SCHEMBL3450953 | 0.69 | KMT2A (0.41) | PDE5ACYP1A2MAPTPOLBCYP2D6 | |
| SCHEMBL6001185 | 0.67 | MEN1 (0.37) | MAPTNPSR1LMNAHSD17B10MEN1 | |
| SCHEMBL3452785 | 0.67 | HSD17B10 (0.45) | CYP1A2MAPTNPSR1CYP2C19HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060128702-A1 | Heterocyclic and bicyclic compounds, compositions and methods | REDDY US THERAPEUTICS, INC. | 2006-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060128702-A1 | Heterocyclic and bicyclic compounds, compositions and methods | HPSE, ENGASE, UGCG | PDE5A 3180/4885CYP1A2 1500/4885CYP3A4 2894/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.