Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.51 |
| ▸ | HPGD | P15428 | 4/20 | 0.51 |
| ▸ | TP53 | P04637 | 6/20 | 0.50 |
| ▸ | DHODH | Q02127 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
| ▸ | CASP7 | P55210 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 5/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6001899 | 0.88 | MAPT (0.55) | ALDH1A1SMN1; SMN2HPGDTP53DHODH | |
| SCHEMBL6001386 | 0.81 | TP53 (0.58) | ALDH1A1SMN1; SMN2HPGDTP53DHODH | |
| SCHEMBL6001935 | 0.80 | LMNA (0.55) | ALDH1A1SMN1; SMN2HPGDTP53MEN1 | |
| SCHEMBL5999859 | 0.78 | LMNA (0.51) | ALDH1A1SMN1; SMN2HPGDDHODHKDM4E | |
| SCHEMBL6001934 | 0.78 | KDM4E (0.64) | ALDH1A1SMN1; SMN2HPGDTP53DHODH | |
| Graveolinine SCHEMBL25286396 | 0.76 | KDM4E (0.66) | ALDH1A1SMN1; SMN2HPGDTP53DHODH | |
| Graveolinine SCHEMBL29411843 | 0.76 | KDM4E (0.66) | ALDH1A1SMN1; SMN2HPGDTP53DHODH | |
| SCHEMBL6001965 | 0.76 | ACP1 (0.61) | ALDH1A1SMN1; SMN2HPGDTP53DHODH | |
| SCHEMBL4857792 | 0.70 | LMNA (0.54) | ALDH1A1SMN1; SMN2HPGDDHODHMEN1 | |
| SCHEMBL10864298 | 0.70 | LMNA (0.52) | ALDH1A1SMN1; SMN2HPGDDHODHMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060128702-A1 | Heterocyclic and bicyclic compounds, compositions and methods | REDDY US THERAPEUTICS, INC. | 2006-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060128702-A1 | Heterocyclic and bicyclic compounds, compositions and methods | HPSE, ENGASE, UGCG | ALDH1A1 2033/4885SMN1; SMN2 3583/4885HPGD 189/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.